July 2025 in “SKIN The Journal of Cutaneous Medicine” This study reported that ritlecitinib was generally well tolerated over 72 months in patients aged 12 and older with alopecia areata, with adverse events like headache and nasopharyngitis observed, and safety outcomes consistent with previous studies.
November 2022 in “Nihon Nyuusankin Gakkaishi/Nihon Nyūsankin Gakkaishi” In a non-blinded study with 12 Japanese participants, applying a lotion containing Lactiplantibacillus plantarum N793 to the scalp for 24 weeks significantly increased hair density and reduced hair loss, with participants reporting improvements in hair thickness and volume, and the treatment deemed safe.
September 2020 in “Journal of Cutaneous Pathology” In this case study, a 69-year-old woman with pityriasis rubra pilaris developed a scarring alopecia with lichen-planopilaris-like features, which responded well to early treatment.
4 citations
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January 2022 in “Dermatology Research and Practice” In this study, methotrexate therapy with or without corticosteroids showed similar efficacy and safety in treating patients with lichen planopilaris, with no significant differences in the primary outcome or adverse effects between the two groups.
17 citations
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October 2023 in “Science Progress” This review discusses the biological properties and potential applications of PCL and barium titanate composites in biomedical fields and reports no new experimental findings; the authors highlight the need for further research.
1 citations
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June 2024 in “British Journal of Dermatology” In this case study, a woman with frontal fibrosing alopecia and associated hyperpigmentation showed significant improvement in skin pigmentation and itch after 9 months of treatment with mycophenolate mofetil, highlighting its therapeutic potential for lichen planus pigmentosus linked to this condition.
16 citations
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October 2014 in “Journal of the American Academy of Dermatology” This study found that oral retinoid therapy may provide clinical improvement in a small percentage of patients with treatment-resistant lichen planopilaris, although it is not commonly used as a first-line treatment.
January 2026 in “Forum Dermatologicum” This study reviewed cases of Graham–Little-Piccardi–Lassueur syndrome and found that topical treatments were generally ineffective, while systemic therapies like prednisone, hydroxychloroquine, and isotretinoin led to partial hair regrowth and disease stabilization, highlighting the importance of early diagnosis and systemic therapy to improve outcomes.
4 citations
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October 2020 in “Journal of oral and maxillofacial surgery” This review discusses the use of Tisseel for stabilizing particulate grafts and reports no new clinical results; the authors emphasize the need for further controlled trials.
13 citations
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June 2011 in “International Journal of Dermatology” This study found that a new lecithinized coal tar formulation did not stain different types of mammalian hair, suggesting it may be promising for treating scalp psoriasis without the drawback of staining.
1 citations
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January 2021 in “Dermatology online journal” This report describes a unique case of linear lichen planus pigmentosus on the face with histological features of lichen planopilaris, which has not been documented before.
January 2024 in “Pharmaceutical journal/The pharmaceutical journal” In this report, NICE has approved ritlecitinib, an oral kinase inhibitor, as the first recommended treatment for severe alopecia areata in individuals aged 12 and older.
1 citations
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May 2022 in “Journal of Drugs in Dermatology” This case report describes a patient with lichen planopilaris who experienced remarkable hair regrowth at a previously scarred area after treatment with low-dose naltrexone and platelet-rich plasma, following minimal response to other therapies.
8 citations
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September 2016 in “Journal of the American Academy of Dermatology” It's important to tell the difference between hair casts, pseudocasts, and nits.
6 citations
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August 1985 in “Archives of dermatology” In this study, two cases of idiopathic hair casts in young girls responded well to 0.025% tretinoin lotion, with analyses suggesting an infrainfundibular origin for the lesions.
January 2026 in “International Journal of Dermatology” In this study, researchers reported that treating alopecia areata patients with ritlecitinib led to progressive improvements in emotional symptoms and activity limitations over 48 weeks, though the post hoc analysis and trial setting suggest caution in interpreting the findings for broader populations.
January 2026 in “Physical Education Health and Social Sciences” This study found that integrating Lactobacillus-rich probiotic nutrition and fractional CO₂ laser therapy with clotrimazole in mucoadhesive hydrogels significantly improved clinical and structural outcomes for women with recurrent vulvovaginal candidiasis, suggesting a promising advanced therapy, though further validation in larger trials is needed.
This chapter provides dermatology trainees with insights on managing lichen planopilaris, emphasizing treating active disease to prevent further hair loss and recommending a tapered course of oral steroids for disease stabilization.
June 2026 in “Journal of health economics and outcomes research” In this study, researchers found that ritlecitinib 50 mg offered a lower cost per responder than baricitinib 2 or 4 mg at both 24 and 52 weeks for treating severe alopecia areata, suggesting potential implications for reimbursement or formulary decisions.
June 2026 in “British Journal of Dermatology” In this case study, a woman with alopecia areata experienced significant hair regrowth after starting ritlecitinib but developed an acneiform eruption, leading to the discontinuation of the drug and subsequent hair loss relapse; the eruption suggests a treatment-limiting adverse effect of JAK inhibitors.
September 2025 in “Value in Health” 3 citations
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November 2023 in “Journal of Investigative Dermatology” Over 45% of patients with alopecia areata benefit from ritlecitinib, mostly within a year.
March 2025 in “Research Square (Research Square)” This study explored the potential of the lysate and lipoteichoic acid from Lactiplantibacillus plantarum APsulloc 331261 to improve scalp seborrheic dermatitis by modulating inflammatory and lipogenesis pathways in vitro, suggesting potential as a natural treatment option.
1 citations
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December 2023 in “Revista médica de Chile” This review examines the dermatologic side effects of lithium, noting it can cause or worsen skin conditions like psoriasis and acne, potentially affecting medication adherence, but reports no new clinical results.
January 2011 in “Yearbook of Dermatology and Dermatologic Surgery” Hair relaxers are linked to reduced cystine levels and potential hair damage.
39 citations
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November 2017 in “PubMed” This case series reported that low-dose naltrexone may benefit patients with lichen planopilaris by reducing scalp symptoms and slowing disease progression, with no adverse effects observed in the patients.
1 citations
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April 2022 in “Clinical Cosmetic and Investigational Dermatology” In this study, a case of lichen amyloidosis on the scalp significantly improved with a 2-month topical treatment using clobetasol propionate/all-trans retinoic acid ointment.
July 2016 in “Dermatologie pro praxi” This article discusses the use of Espumil foam base in pharmacies for preparing dermatological medications and reports no new clinical results.
In this case study, a patient with refractory oral lichen planus experienced marked improvement within one month of daily treatment with baricitinib, contributing to the evidence supporting the use of JAK inhibitors for lichen planus.
April 2023 in “IP Indian journal of clinical and experimental dermatology” This article reviews the pathogenesis, complications, and management of lichen planus, especially its persistent oral form, and highlights the need for further prospective studies.