Review Use of Tisseel, a Fibrin Sealant, for Particulate Graft Stabilization
October 2020
in “
Journal of oral and maxillofacial surgery
”
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Studysummary This review discusses the use of Tisseel for stabilizing particulate grafts and reports no new clinical results; the authors emphasize the need for further controlled trials.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The article reviewed the use of Tisseel, a fibrin sealant, for stabilizing particulate bone grafts, comparing it with PRP, L-PRF, and resorbable membranes. It highlighted Tisseel's advantages, such as its ability to maintain graft shape longer due to aprotinin, ease of use without requiring blood draw or centrifuge, and comparable cost to other methods. Two case reports demonstrated successful ridge augmentation using Tisseel. However, the authors noted limitations, including a small sample size and incomplete treatment in one case, concluding that more clinical trials are needed to validate Tisseel's superiority.
