research Profile of Tofacitinib Citrate and Its Potential in the Treatment of Moderate-to-Severe Chronic Plaque Psoriasis
Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.
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research Procyanidin B-2 Extracted from Apples Promotes Hair Growth: A Laboratory Study
Apple extract called procyanidin B-2 was found to greatly increase hair growth.
research Vitamin D Receptor Polymorphisms and Polycystic Ovary Syndrome: A Systematic Review
The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.
research The Transdermal Inhibition of Melanogenesis by a Cell-Membrane-Permeable Peptide Delivery System Based on Poly-Arginine
A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.
research Skin: Basic Structure and Function
The skin is a complex barrier that protects the body, regulates temperature, and helps with immune responses.
research Recent Advances on Skin-Resident Stem/Progenitor Cell Functions in Skin Regeneration, Aging, and Cancers and Novel Anti-Aging and Cancer Therapies
New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
research Food Deprivation-Induced Expression of Minoxidil Sulfotransferase in the Hypothalamus Uncovered by Microarray Analysis
Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.
research Basics of Androgen Synthesis and Action
Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.
research The Bright Side of Fibroblasts: Molecular Signature and Regenerative Cues in Major Organs
Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
research Evaluation of Affective Temperament and Anxiety–Depression Levels of Patients with Polycystic Ovary Syndrome
Women with PCOS tend to have higher anxiety and depression levels compared to healthy women.
research CD98hc (SLC3A2) Regulation of Skin Homeostasis Wanes With Age
CD98hc's role in skin health decreases with age.
research Leydig Cell Hyperplasia and Adenomas in Mice Treated with Finasteride, a 5α-Reductase Inhibitor: A Possible Mechanism
High doses of finasteride cause cell growth and tumors in mice.
research Pathogenesis and Treatment Options for Chemotherapy-Induced Alopecia: A Systematic Review
Scalp cooling is the most effective FDA-approved method to prevent chemotherapy-induced hair loss, but more research is needed for other treatments.
research Neuroactive Gonadal Drugs for Neuroprotection in Male and Female Models of Parkinson's Disease
Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.
research Straight Hair Associated with Interferon-Alpha Plus Ribavirin in Hepatitis C Infection
ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.
research Cell Wall-Associated Root Hair Specific 10, a Proline-Rich Receptor-Like Kinase, Is a Negative Modulator of Arabidopsis Root Hair Growth
ROOT HAIR SPECIFIC 10 (RHS10) reduces the length of root hairs in Arabidopsis plants.
research Middle East Medicinal Plants in the Treatment of Diabetes: A Review
Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.
research FOXN1 Deficient Nude Severe Combined Immunodeficiency
FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.
research A Critical Assessment of the Evidence for Low-Level Laser Therapy in the Treatment of Hair Loss
The evidence for using Low-Level Laser Therapy for hair loss is limited and more thorough research is needed.
research STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction
STAT5 activation is crucial for starting the hair growth phase.
research Use of Insulin-Sensitizing Agents in Patients With Polycystic Ovary Syndrome
Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.
research Systemic Lupus Erythematosus: Definitions, Contexts, Conflicts, Enigmas
The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.
research Oxidative Stress Management in the Hair Follicle: Could Targeting NRF2 Counter Age-Related Hair Disorders and Beyond?
Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
research Characterization of Cell Cycle Arrest and Terminal Differentiation in a Maximally Proliferative Human Epithelial Tissue: Lessons from the Human Hair Follicle Matrix
CIP/KIP proteins help stop cell division and support hair growth.
research Keratinocyte Stem Cells but Not Melanocyte Stem Cells Are the Primary Target for Radiation-Induced Hair Graying
Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.
research Cetuximab-Associated Elongation of the Eyelashes
Cetuximab can cause eyelash growth, which is rare but manageable.
research What Does Acne Genetics Teach Us About Disease Pathogenesis?
Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.
research Wound Healing in Development: Mechanisms and Regulation
Wounds heal without scarring in early development but later result in scars, and studying Wnt signaling could help control scarring.
research Dormancy in the Stem Cell Niche
Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.
research Differential Expression Analysis of Balding and Nonbalding Dermal Papilla MicroRNAs in Male Pattern Baldness Using a MicroRNA Amplification Profiling Method
Certain microRNAs are more common in balding areas and might be involved in male pattern baldness.