45 citations
,
December 2007 in “The FASEB journal” This study demonstrated that hair follicle bulge stem cells can form epidermis in a tissue-engineered skin model, highlighting the significance of K5/K17 filaments in slow-cycling stem cell subsets.
This report describes a case where a young woman developed Kerion Celsi, a fungal skin infection, potentially linked to the use of a tretinoin, minoxidil, and betamethasone valerate lotion.
January 2019 in “대한피부과학회지” This study found that patients with kerion responded well to antifungal treatments, with a lower dose of prednisolone effectively reducing inflammation when systemic corticosteroids were needed.
8 citations
,
July 2004 in “Journal of morphology” This study explored the structure and keratin composition of marsupial hairs, finding similarities in keratin localization to hairs in placental mammals, and highlighting potential roles of trichohyalin and transglutaminase during hair development and shedding.
35 citations
,
October 2002 in “Biochemical and Biophysical Research Communications” This study reports that K7 expression patterns observed in mice are similar to those in humans, revealing previously unreported expression in the gastrointestinal tract, tongue, and various "hard" epithelial tissues.
3 citations
,
January 2022 in “Medical Mycology Journal” This study observed Malassezia hyphae in the keratotic plugs of healthy individuals, which contrasts with previous findings of these hyphae primarily in lesions of pityriasis versicolor patients.
This study examines the structure of the "sinuskissen" in cat hair follicles, revealing it as a loose connective tissue susceptible to changes in aqueous flow, and describes its variable three-dimensional shapes.
February 2023 in “Journal of the European Academy of Dermatology and Venereology”
34 citations
,
August 1966 in “Experimental cell research” This study examined developing hair cortex with electron microscopy and found that keratin fibrils form between specific regions in hair follicles and aggregate into twisted cables.
41 citations
,
January 1992 in “Journal of medical genetics” This study described seven male patients and six female carriers of keratosis follicularis spinulosa decalvans, highlighting distinct dermatological and ophthalmic markers including follicular hyperkeratosis and corneal dystrophy.
April 2025 in “Veterinary Dermatology” This study observed that dermoscopy is a useful technique for distinguishing between infundibular keratinising acanthoma and follicular cysts in dogs, with specific dermoscopic features noted for each.
139 citations
,
December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified a new type II cytokeratin, named K6hf, exclusively expressed in the companion layer of the human hair follicle, distinguishing it from other keratins and suggesting a unique biochemical role.
5 citations
,
March 1943 in “Archives of Dermatology and Syphilology” This report describes a rare case of a woman with keratosis follicularis presenting with extensive alopecia and nail abnormalities, adding to the medical literature due to its unusual presentation.
186 citations
,
December 2012 in “Current opinion in cell biology” This review discusses the recent advancements in understanding how keratins influence cytoarchitecture, cell dynamics, and disease processes but reports no new clinical results; the authors highlight its roles in development and diseases like cancer.
7 citations
,
August 1984 in “Mycoses” This study found that hair regrowth after griseofulvin treatment for kerion Celsi was significantly reduced in previously affected areas compared to unaffected areas in 18 patients.
48 citations
,
July 1993 in “Archives of Dermatological Research” Merkel cells are abundant in facial vellus hair follicles, especially during the anagen phase.
50 citations
,
July 2008 in “British Journal of Dermatology”
14 citations
,
June 2019 in “BMC infectious diseases” This study presents the first reported case of kerion-type scalp mycosis caused by Aspergillus protuberus, emphasizing the importance of mycological examination when diagnosing unusual scalp infections, especially in children.
6 citations
,
December 2011 in “Clinical and Experimental Dermatology” A woman developed rare, unexplained curly hair on her scalp and eyelashes.
April 2019 in “Journal of Investigative Dermatology” In this report, the potential connection between Merkel cell carcinoma and Curvularia lunata infection in an elderly patient is discussed, highlighting the need for precise diagnostic methods and suggesting that surgery combined with the antifungal voriconazole may be a viable treatment option.
January 2025 in “Journal of Fungi” This case report highlights the importance of early mycological diagnostics, supported by dermoscopy and ultraviolet-enhanced fluorescence dermoscopy, in preventing scarring from kerion celsi-associated hair loss in children.
54 citations
,
November 1994 in “Differentiation” This study found that trichohyalin is expressed in various normal and pathological epithelia beyond hair follicle cells, where it is uniquely associated with filaggrin, suggesting a specific role in aggregating K6/K16-containing intermediate filaments.
November 2022 in “Journal of Investigative Dermatology” This study found that DermaCult™ Keratinocyte Expansion Medium allows for significantly extended growth of human epidermal keratinocytes while maintaining their differentiation potential.
This article discusses the structure and protective function of pangolin scales, emphasizing their composition of α-keratins and β-keratins, and highlights evolutionary keratin diversification in tetrapods; it reports no new empirical findings.
6 citations
,
January 2023 in “Medical Mycology Journal” In this case study of a 64-year-old woman with kerion celsi caused by Microsporum canis, treatment with the oral antifungal fosravuconazole resulted in symptom resolution without scarring or side effects over 12 weeks, suggesting its potential effectiveness for various dermatomycoses.
June 2026 in “BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY” This review summarizes the clinical, dermoscopic, and histopathological features of keratoacanthoma and discusses treatment strategies, emphasizing dermoscopy's role in diagnosis and individualized treatment planning.
January 2022 in “Clinical Cases in Dermatology” This article describes pilar cysts, common dermal cysts often seen in young women, which typically require surgical removal.
6 citations
,
May 2000 in “Pediatric Dermatology” This article discusses a case study supporting the reclassification of KID syndrome as an ectodermal dysplasia, introducing a potential treatment combination that may alleviate symptoms in affected patients.
March 2026 in “South Asian Research Journal of Medical Sciences” In this case study, a 7-year-old boy with kerion celsi experienced persistent inflammation even after microbiological clearance; dermoscopic-guided removal of hair and keratin debris improved his condition, suggesting a novel inflammatory mechanism involving granulomatous response to keratinous debris in tinea capitis.
40 citations
,
June 2013 in “Scientific Reports” This study found an association between a splice site variant in the KRT71 gene and curly hair in Selkirk Rex cats, identifying a significant locus on chromosome B4.