32 citations
,
January 2020 in “Journal of Molecular Histology” This research identified K31 as a new marker for distinguishing clear secretory cells in human eccrine sweat glands, aiding in differentiating between distinct cell types within these glands.
61 citations
,
February 1982 in “Cell and Tissue Research” 3 citations
,
January 2021 in “Therapeutic advances in infectious disease” This report describes a 9-year-old girl with a scalp kerion treated successfully with terbinafine and ketoconazole shampoo, leading to hair regrowth after two months.
25 citations
,
August 2020 in “Experimental eye research/Experimental Eye Research” This review discusses cornea-specific keratin expression patterns in human and mouse development and reports no new experimental results; it highlights the need for investigating keratin mutations' role in pathology.
36 citations
,
December 2004 in “British Journal of Dermatology” This case study reports a peculiar variant of an epidermal cyst in a patient, featuring unique characteristics like brownish, lumpy contents resembling bone marrow.
13 citations
,
March 2011 in “Acta Paediatrica” This case report describes a 5-year-old girl who developed kerion celsi from an untreated scalp infection, likely contracted from a guinea pig, leading to significant hair loss and the need for a wig.
1 citations
,
October 2024 in “BMC Pediatrics” In this study, researchers analyzed data from 132 hospitalized kerion patients over 11 years, mostly children under 11 from rural areas, and noted a significant male predominance and frequent animal contact as potential transmission factors.
32 citations
,
April 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” This study demonstrates that keratin K2 is crucial for proper keratinocyte structure and function in specific mouse skin areas, and its deficiency leads to cellular aggregates and skin abnormalities.
10 citations
,
July 1984 in “British Journal of Dermatology” In this study, the staining properties of two types of cysts, epidermal and pilar, were found to differ, supporting their origins from the epidermis and the trichilemmal hair follicle layer, respectively.
44 citations
,
August 1990 in “PubMed” This study provides evidence for K1 and K10 derivatives' presence in the inner root sheath and hair cuticle, suggesting that these hair follicle parts may follow familiar keratinization principles.
7 citations
,
July 2019 in “The Journal of Dermatology” This case report describes an 18-year-old male with kerion celsi from Trichophyton tonsurans infection whose condition improved with terbinafine treatment, and highlights that although IL-17A expression increased in skin lesions, it was associated with disrupted antimicrobial peptide expression and severe inflammation, causing tissue damage.
3 citations
,
September 2020 in “Case reports in dermatological medicine” This case report described a misdiagnosed kerion in a 10-year-old child initially treated as a bacterial abscess, leading to unnecessary surgery and residual scarring alopecia.
2 citations
,
June 2001 in “Medical Electron Microscopy” This study observed that the keratinization pattern of trichilemmal cysts in two Japanese women may originate from the proliferation of the outer root sheath in the follicular isthmus of anagen hairs.
28 citations
,
September 2013 in “European Journal of Histochemistry” This study demonstrates a varied distribution of keratins in the epidermis of the Malayan pangolin, suggesting evolutionary adaptations related to their distinctive scales.
22 citations
,
January 2009 in “Medical mycology” In this case report, researchers identified Arthroderma vanbreuseghemii as the cause of a familial fungal infection, which was successfully treated with itraconazole and topical terbinafine cream.
3 citations
,
June 2021 in “Case Reports in Infectious Diseases” This case study reports that a 9-year-old Nepalese boy with tinea capitis successfully recovered with systemic antifungal therapy, though experienced focal alopecia without recurrence at a two-year follow-up.
38 citations
,
December 2006 in “Journal of Investigative Dermatology” Keratin patterns in hair follicles help understand hair growth and potential hair and nail disorders.
1 citations
,
February 2005 in “The Journal of Laryngology & Otology” This case report describes a 19-year-old farmer who experienced difficulty breathing due to a fungal infection in the neck, successfully treated with antibiotics and antifungal medications.
36 citations
,
January 1994 in “Cell and Tissue Research” 6 citations
,
August 2016 in “Journal of Visualized Experiments” This article describes a method using the CUBIC protocol to clarify and visualize molecular and cellular interactions in mouse skin biopsies at single cell resolution, but does not provide new biological findings.
482 citations
,
June 1979 in “Proceedings of the National Academy of Sciences” This study demonstrated that keratin is widely present in various epithelial cells, providing structural strength and potential insights into the origin of cell lines.
1398 citations
,
May 2008 in “Histochemistry and Cell Biology” This review summarizes the cell type distribution and functional significance of human keratins, emphasizing their roles in tumor diagnosis and potential clinical applications, and reports no new clinical findings.
27 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” 33 citations
,
October 2012 in “Journal of Morphology” This study identified the distribution of keratin-associated proteins during cornification in the epidermis of reptiles, revealing unique structural characteristics in sauropsid keratin proteins compared to other vertebrates.
13 citations
,
May 2001 in “Current problems in dermatology” Keratin proteins in epithelial cells are dynamic and crucial for cell processes and disease understanding.
8 citations
,
May 2005 in “The American journal of dermatopathology/American journal of dermatopathology” This study observed unique ultrastructural changes in a 4-year-old girl with pili trianguli et canaliculi that may affect hair shaft surface characteristics due to inner root sheath alterations.
26 citations
,
July 1993 in “Journal of Investigative Dermatology”
April 2018 in “Journal of Investigative Dermatology” This study found that keratin filament networks in SG1 cells of mice undergo dynamic changes during cornification, impacting the barrier function of the stratum corneum.
1 citations
,
November 2024 in “Romanian Journal of Morphology and Embryology” This overview examines the biology, origin, structure, and function of various cells and structures, such as the blood-retinal barrier and Merkel cells, and discusses their roles in disease pathogenesis, along with recent findings related to the lymph nodes' paracortex.
45 citations
,
December 2007 in “The FASEB journal” This study demonstrated that hair follicle bulge stem cells can form epidermis in a tissue-engineered skin model, highlighting the significance of K5/K17 filaments in slow-cycling stem cell subsets.