Trichophyton Tonsurans-Induced Kerion Celsi with Decreased Defensin Expression and Paradoxically Increased Interleukin-17A Production

    July 2019 in “ The Journal of Dermatology ”
    Yoshihiro Gotō, Takahiro Suzuki, Yoko Suzuki … Y. Tokura
    Studysummary This case report describes an 18-year-old male with kerion celsi from Trichophyton tonsurans infection whose condition improved with terbinafine treatment, and highlights that although IL-17A expression increased in skin lesions, it was associated with disrupted antimicrobial peptide expression and severe inflammation, causing tissue damage.
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    Research cited in this study 2

    1. Diagnosis and Management of Tinea Infections PubMed · 2014
    2. British Association of Dermatologists' Guidelines for the Management of Tinea Capitis 2014 British journal of dermatology/British journal of dermatology, Supplement · 2014