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The p.P25L mutation in the KRT5 gene causes a rare skin condition that worsens over time and may lead to hair loss starting in young adulthood.

Combining skin tissue pathology with genetics has greatly improved the diagnosis and understanding of certain skin diseases.

Proteomics combined with other technologies can lead to a better understanding of skin diseases.

Certain genes are linked to the quality of cashmere in goats.

Sebaceous glands can heal and regenerate after injury using their own stem cells and help from hair follicle cells.

Scientists used stem cells to create a model of the skin disease Epidermolysis Bullosa simplex, which helped them understand its molecular mechanisms and could aid in finding treatments.

Scientists found 53 keratin genes in yaks that are important for hair growth and share similarities with those in other animals.

Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.

Estrogen therapy helped regrow hair in a bald man.

Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.

Harlequin mutant mice have hair loss due to low AIF protein levels and retroviral element activity.

Myoepithelial cells can repair airways after severe injury.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.

Certain mature cells in mouse lungs can turn back into stem cells to aid in tissue repair.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

New treatments targeting specific genes show promise for treating keratin disorders.

Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.

Scientists created stem cells that can grow hair and skin.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.