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WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.

Targeting NETs may help reduce fibrosis in Crohn's disease.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Hair loss in autoimmune blistering skin diseases varies and may regrow with disease control.

Acupuncture may improve reproductive and metabolic functions in PCOS without negative side effects, but more research is needed to confirm its effectiveness.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.

External factors can cause skin cancer cells that usually don't spread to grow and form tumors in mice.

TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.

New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Mice without certain skin enzymes have faster hair growth and bigger eye glands.

Lipin-1 is important for skin cell differentiation and skin barrier function.

Higher levels of the DP2 receptor may lead to hair loss.

Women with scarring alopecia are less likely to have used hormone replacement therapy or oral contraceptives compared to those with female pattern hair loss.

Calcium signals and SHH guide the direction of feather growth in chicken skin.

Eating grape powder may reduce the severity of skin allergy symptoms.

Certain zinc transporters are essential for healthy skin and managing zinc in the body could help treat skin problems.

Increasing sebum production might help reduce fat and improve metabolism.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Loss of keratin K2 causes skin problems and inflammation.

The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.

3-Deoxysappanchalcone helps human hair cells grow and stimulates hair growth in mice by affecting certain cell signaling pathways.