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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Blocking YAP/TAZ could be a new way to treat skin cancer.

Inhibiting Zyxin may help treat androgenetic alopecia by promoting hair growth.

White blood cells and their traps can slow down the process of new hair growth after a wound.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

The pituitary gland functions normally even after losing most SOX2+ stem cells.

Scientists can mimic hair disorders by altering genes in lab-grown human hair follicles, but these follicles lack some features of natural ones.

Dermal Papilla Cells grown in 3D and with stem cells better mimic natural hair growth conditions than cells grown in 2D.

The 3D-SeboSkin model effectively simulates Hidradenitis suppurativa and is useful for future research.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.

Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.

Loss of Fz6 disrupts hair follicle and associated structures' orientation.

Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.

Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.

Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.

Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.

The study found that tight junctions reach the top layer of the skin's stratum granulosum, not just the second top layer as previously thought.

Frog skin cells need the protein desmoplakin for proper development and cell layer formation.