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High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.

Higher minoxidil doses in dogs cause faster heart rate, lower blood pressure, and heart issues.

Cell-based therapies show promise for treating Limbal Stem Cell Deficiency but need more research.

Scalp flaps are stiffer than skin from other body areas, which helps in planning reconstructive and cosmetic head surgeries.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

The document concludes that veterinary dermatologists need more experience and a better approach to treating skin diseases in nonhuman primates.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.

Hair's strength and flexibility come from its protein structure and molecular interactions.

The cause of alopecia areata is likely a mix of genetics, immune system issues, and environmental factors, with more research needed to understand it fully.

Tofacitinib nanoparticles can safely and effectively treat alopecia areata by targeting hair follicles.

Start acne treatment early to prevent scarring, consider antibiotic resistance, use maintenance therapy, and manage side effects carefully.

Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.

New drugs targeting DNA enzymes show promise for cancer treatment but have side effects like immune system suppression and hair loss.

Graphene oxide helps deliver a skin healing agent over time, improving skin and hair follicle regeneration.

Lecithin-encapsulated resveratrol nanoparticles could be a safe and effective anti-cancer treatment.

Removing anthrax toxin receptor 1 in pigs prevents Senecavirus A infection and causes a rare disease similar to GAPO syndrome.

Androgens reduce BMP2, which weakens the ability of certain cells to help hair stem cells become different types of cells.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Skin patterns form through molecular signals and genetic factors, affecting healing and dermatology.

Understanding hair surface properties is key for effective hair care products.

The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.

Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.

JAGGED1 could help regenerate tissues for bone loss and heart damage if delivered correctly.

Pueraria mirifica extract may help treat benign prostatic hyperplasia.

Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.

Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.

Liposomes show promise in cancer treatment by delivering drugs with less toxicity and improved effectiveness.

A device was made in 2008 to measure hair loss severity. Other findings include: frizzy mutation in mice isn't related to Fgfr2, C/EBPx marks preadipocytes, Cyclosporin A speeds up hair growth in mice, blocking plasmin and metalloproteinases hinders healing, hyperbaric oxygen helps ischemic wound healing, amniotic membranes heal wounds better than polyurethane foam, rhVEGF165 from a fibrin matrix improves tissue flap viability and induces VEGF-R2 expression, and bFGF enhances wound healing and reduces scarring in rabbits.

Wharton’s Jelly stem cells from the umbilical cord improve skin healing and hair growth without scarring.