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Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

Meis1 is crucial for skin health and tumor development.

Understanding and tracking our body's natural daily rhythms could help improve heart health.

The VEGF +405G allele may increase the risk of PCOS in South Indian women.

Mice with CBS deficiency are healthier on a low-methionine diet.

Astaxanthin is a safe antioxidant that may improve heart, skin, eye health, and physical performance, and help manage chronic diseases.

COVID-19 can cause various skin problems, including reactions to protective gear and medication, with different rates reported worldwide, and more research is needed to fully understand these skin issues.

PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Dermatologists should screen for and manage psychological issues in patients with skin conditions to improve their quality of life.

Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.

Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.

A family got a fungal infection from a boy who had contact with rabbits, but they all recovered with treatment.

Bimatoprost can cause longer, thicker, darker eyelashes and eyebrows.

A new storage solution may increase hair transplant graft survival.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Hydroxychloroquine showed some potential, but overall, the three drugs had limited success in treating lupus in dogs.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

The document concludes that there are still unknowns about the effectiveness, risks, and detection of performance-enhancing drugs, and doping remains a challenge.

Methionine restriction works better than betaine for treating CBS deficiency symptoms in mice.

Severe digestive issues in DRESS need early endoscopy for better treatment.

High glucocorticoids cause pancreatic malfunction and malabsorption, reversible with enzyme supplements.