research Human Hair Proteins as Natural Reactive Oxygen Species Scavengers for In Vitro Applications
Human hair proteins, especially keratins, can protect cells from oxidative stress in lab settings.
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research Human Hair Keratin Gradient Metallogel and Their Applications for Wound Healing
The research developed a human hair keratin and silver ion hydrogel that could help heal wounds.
research Electrophoretic Variability in Human Head Hair: Polyacrylamide Gel Electrophoresis of Hair Proteins in the Presence of Sodium Dodecyl Sulfate and Urea
Human head hair proteins can be typed into eight distinct patterns, useful for genetic and forensic investigations.
research Human Hair Keratin-Based Hydrogels in Regenerative Medicine: Current Status and Future Directions
Human hair keratin hydrogels show promise for use in regenerative medicine.
research Rational Design of Human Hair Keratin-Driven Proteins for Hair Growth Promotion
RK81 can help promote hair growth.
research Love Is in the Hair: Arginine Methylation of Human Hair Proteins as Novel Cardiovascular Biomarkers
Human hair protein modifications could potentially indicate heart disease risk.
research DNA Dioxygenases Tet1/2/3 Control Hair Matrix Keratinocyte Differentiation and Hair Shaft Shape via Regulation of Hair Keratin Gene Expression
The enzymes Tet1, Tet2, and Tet3 are important for the development of hair follicles and determining hair shape by controlling hair keratin genes.
research Biochemical Evidence That Small Proline-Rich Proteins and Trichohyalin Function in Epithelia by Modulation of the Biomechanical Properties of Their Cornified Cell Envelopes
Small proline-rich proteins and trichohyalin help make epithelial tissues tougher and more flexible.
research Characterization of the Proteins of Guinea-Pig Hair and Hair-Follicle Tissue
This study focused on characterizing the proteins in guinea-pig hair and hair-follicle tissue to understand protein synthesis in hair follicles. Five groups of reduced carboxymethylated proteins were identified, with group 1B proteins being unique to the follicle, likely originating from the medulla and inner-root-sheath layers. Most hair and follicle proteins shared similar properties, but quantitative differences were observed: follicle extracts had more group 2 proteins and fewer group 3 and 4 proteins compared to hair extracts. Additionally, follicle group 4 proteins had more low molecular weight proteins and fewer high molecular weight proteins than hair group 4 proteins. These differences were analyzed in the context of keratin protein synthesis, with group 1B proteins potentially being precursors to mature medulla and inner root sheath proteins.
research Solubility of Structurally Complicated Materials: Hair
Hair is hard to dissolve because of its complex proteins, but certain solvents that break specific bonds and hydrate can do it.
research Molecular Genetics of Inherited Disorders of Epidermal Keratins
Mutations in keratin genes cause skin disorders, but new treatments show promise.
research Investigation of the Damage on the Outermost Hair Surface Using ToF-SIMS and XPS
Bleaching hair causes significant damage by breaking down proteins and fatty acids.
research The In Vitro Assembly of Hair Follicle Keratins: Comparison of Cortex and Companion Layer Keratins
Different conditions affect how hair proteins assemble, and certain mutations can change their structure.
research A Dispute Between the Cavendish and Caltech: The Emergence and Ubiquity of the Alpha-Helix
The alpha-helix was confirmed as a key structure in proteins.
research The Epidermis: Rising to the Surface
The document concludes that recent research has improved understanding of skin diseases and the balance between cell growth and differentiation in the epidermis.
research Unique Amino Acid Signatures That Are Evolutionarily Conserved Distinguish Simple-Type, Epidermal, and Hair Keratins
Different keratin types have unique amino acid patterns that are evolutionarily conserved.
research Skin Organoids Derived From NCSTN Mutated Patient-Induced Pluripotent Stem Cells Recapitulate Hidradenitis Suppurativa Pathogenic Hallmarks
Skin organoids with NCSTN mutation show changes in hair follicle development and higher inflammation, key features of Hidradenitis Suppurativa.
research Pathological Modeling of Epidermolysis Bullosa Simplex Using Induced Pluripotent Stem Cells
Scientists used stem cells to create a model of the skin disease Epidermolysis Bullosa simplex, which helped them understand its molecular mechanisms and could aid in finding treatments.
research Understanding the Effect on Hair Fibers of Coloring and Bleaching Formulations Using High Pressure Differential Scanning Calorimetry
Hair coloring and bleaching can permanently break down hair protein and temporarily change its properties.
research Isolation of Intermediate Filament Assemblies from Human Hair Follicles
Researchers isolated and identified structural components of human hair follicles, providing a model for studying hair formation.
research Attenuated Total Reflection Fourier Transform Infrared Spectroscopy Analysis of Human Hair Fiber Structure
Human hair has different protein structures in its cuticle and cortex.
research Nutrition of Women with Hair Loss During Menopause
Eating a balanced diet with specific nutrients is important for menopausal women to manage hair loss.
research Formulation and Evaluation of Hair Growth Serum from Hibiscus Flowers and Leaves
The serum with hibiscus and other natural ingredients improves hair growth and quality.
research iTRAQ-Based Quantitative Proteomics Revealing the Therapeutic Mechanism of a Medicinal and Edible Formula YH0618 in Reducing Doxorubicin-Induced Alopecia by Targeting Keratins and TGF-β/Smad3 Pathway
YH0618 helps reduce chemotherapy-induced hair loss by targeting specific proteins and pathways.
research Using the Frog Embryonic Epidermis as a Model to Study Desmosome Function During Development
Frog skin cells need the protein desmoplakin for proper development and cell layer formation.
research Epithelial Loss of Mitochondrial Oxidative Phosphorylation Leads to Disturbed Enamel and Impaired Dentin Matrix Formation in Postnatal Developed Mouse Incisor
Mitochondrial problems in tooth cells lead to bad enamel and dentin development in mice.
research Clinical Snippets: Research Findings in Dermatology
New findings suggest potential treatments for melanoma, hyperpigmentation, hair defects, and multiple sclerosis, and show skin microbiome changes don't cause atopic dermatitis.
research How a Bird Gets Its Feathers: Insights from Chromatin Looping
Feather patterns are influenced by enhancers and chromatin looping, and the structure of protein complexes important for hair growth has been detailed.
research Clinical Snippets: Insights into Dermatological Studies
Some cells may slow melanoma growth, a protein could affect skin pigmentation, a gene-silencing method might treat hair defects, skin bacteria changes likely result from eczema, and a defensin protein could help treat multiple sclerosis.
research In Vitro Growth and Differentiation of Epithelial Cells Derived from Post-Embryonic Hair Follicles
The study investigated the in vitro growth and differentiation of epithelial cells from post-embryonic hair follicles of young rats. Cell aggregates formed within the first 2 days of culture, with higher cell densities accelerating this process. These aggregates primarily consisted of epithelial cells, though some mesenchymal (fibroblast) cells were also present. Citrulline was found in the cultured cell proteins, and electrophoretic analysis revealed hair cortical keratin. However, contrary to previous findings, these proteins were not synthesized during the culture period.