research The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed
The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
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research Teriflunomide and Its Mechanism of Action in Multiple Sclerosis
Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.
research The PDGF/PDGFR Pathway as a Drug Target
The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
research Fetal Alcohol Syndrome: Current Status of Pathogenesis
The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.
research Alopecia Areata: A Multifactorial Autoimmune Condition
Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
research Therapeutic Anti-Inflammatory Potential of Formyl-Peptide Receptor Agonists
Formyl-peptide receptor agonists could be new anti-inflammatory drugs.
research Human αβ and γδ T Cells in Skin Immunity and Disease
Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.
research Expression of Calcium-Binding S100 Proteins A4 and A6 in Regions of the Epithelial Sac Associated with the Onset of Hair Follicle Regeneration
S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.
research Next Generation Human Skin Constructs as Advanced Tools for Drug Development
Advanced human skin models improve drug development and could replace animal testing.
research Dissecting the Microenvironment Around Biosynthetic Scaffolds in Murine Skin Wound Healing
Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.
research Structural Study of Polymorphs and Solvates of Finasteride
Different forms of hair loss drug can improve effectiveness.
research The Role of Lymphocytes in the Development and Treatment of Alopecia Areata
Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
research What Should It Take to Describe a Substance or Product as 'Sperm-Safe'?
Products should be called 'sperm-safe' only after thorough, well-designed tests.
research Alopecia Areata Is Characterized by Dysregulation in Systemic Type 17 and Type 2 Cytokines, Which May Contribute to Disease-Associated Psychological Morbidity
Alopecia areata involves immune system imbalances that may lead to depression and anxiety.
research Fluoroquinolone-Induced Serious, Persistent, Multisymptom Adverse Effects
Some people experience severe, long-lasting side effects from fluoroquinolone antibiotics, leading to the recommendation of limited use and increased awareness of these risks.
research The Effects of Androgens on T Cells: Clues to Female Predominance in Autoimmune Liver Diseases
Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.
research Thyroid Diseases and Skin Autoimmunity
Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.
research Short-Term Responses of Soybean Roots to Individual and Combinatorial Effects of Elevated CO2 and Water Deficit
Elevated CO2 can lessen the negative impact of water shortage on soybean roots and affects specific genes.
research Investigation of Intermolecular Interactions in Finasteride Drug Crystals in View of X-ray and Hirshfeld Surface Analysis
Finasteride crystals are held together by hydrogen bonds and weak interactions, forming synthon pseudopolymorphs.
research The Association Between HDAC9 Gene Polymorphisms and Stroke Risk in the Chinese Population: A Meta-Analysis
Certain variations of the HDAC9 gene can increase or decrease stroke risk in the Chinese population.
research Aloe Vera Gel Effect on Skin and Pharmacological Properties
Aloe Vera gel helps heal skin, treats skin conditions, and can stimulate hair growth due to its various healing properties.
research Anti-Androgen Therapy in Female Adult Acne
Anti-androgens are safe and effective for treating moderate to severe adult female acne.
research The Case for Case Reports
Case reports are important in medical science for discovering drugs and identifying rare conditions, despite their limitations.
research Trichotillomania – Therapeutic Possibilities
Cognitive-behavioral therapy with habit reversal training is the most effective treatment for trichotillomania.
research Microemulsion Formulation of Combination of Virgin Coconut Oil and Rice Bran Oil for Hair Growth
The combination of virgin coconut oil and rice bran oil in the FIII formula promoted hair growth effectively.
research Activity of Hair Tonic Nanoemulsion with Candlenut Oil on Mice
Candlenut oil hair tonic helps mice grow hair, with higher oil concentration giving better results.
research Development And Optimization Of Celery Leaf Gel (Apium Graveolens L.) Based On Chitosan-Alginate Using Box-Behnken Method For Hair Growth
Celery extract didn't significantly boost hair growth in the gel.
research Formulation and Evaluation of Antifungal Activity of Anti-Dandruff Gel Shampoo with Lemongrass Oil (Cymbopogon citratus)
Lemongrass oil in gel shampoo effectively fights dandruff, with 10% concentration being the most effective.
research Shushing Down the Epigenetic Landscape Towards Stem Cell Differentiation
The document concludes that pig iPSCs show promise for transplant therapies and the field is advancing in controlling cell behavior for biology and medicine.
research Epidermal Growth Factor Receptor Mutant T790M-L858R-V948R Inhibitor from Calophyllum Inophyllum L. Leaf as Potential Non-Small Cell Lung Cancer Drugs
A compound from Calophyllum inophyllum L. leaf may help treat non-small cell lung cancer.