Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that loss of Ptch1 function in mouse skin's basal cells is sufficient to rapidly induce tumors resembling human basal cell carcinoma, suggesting Ptch1 as a key tumor suppressor.

This study found that activating both PKM2 and Wnt/β-catenin signaling enhanced hair re-growth and HFSCs proliferation in mice, suggesting a potential treatment strategy for alopecia.

Finasteride and dutasteride's effects are mainly due to target binding saturation and slow enzyme turnover.

This study found that loss of the Pten gene in Lgr5+ hair follicle stem cells promoted squamous cell carcinoma formation through the Akt/β-catenin signaling pathway.

This study found that DermaCult™ Keratinocyte Expansion Medium allows for significantly extended growth of human epidermal keratinocytes while maintaining their differentiation potential.

This research investigates the potential of green tea leaves and herb gotukola for promoting hair growth, but it reports no new experimental results.

This study found that while GPT-4 shows high accuracy and efficiency in clinical decision making, physicians' critical thinking and lifelong learning skills remain essential, particularly in addressing and interpreting AI errors in medical settings.

In this study, DataDerm revealed that from 2016 to 2022, a majority of patients diagnosed with keratinocyte carcinoma were male, predominantly white, and commonly between 56-75 years old, with most living in urban areas and having a history of non-melanoma skin cancer.

In this study, herbal hair tonic made from Usada Bali ingredients significantly increased hair growth in mice without causing skin irritation compared to a negative control.

This study found that DHT induces apoptosis in human keratinocyte cells via ERK activation, independently of androgen receptors and the Wnt/β-catenin pathway.

This study explored the localization of phenolsulphotransferase in human embryonic and fetal kidneys, finding distinct patterns of PST immunoreactivity in developing mesonephric and metanephric structures over time.

This study found that Phaeodactylum tricornutum extract enhanced hair follicle cell proliferation, indicated by increased keratin and ERK1/2 signaling, suggesting its potential for hair care applications.

This study identified the Itpr3 gene as responsible for the tufted hair loss phenotype in the BTBR mouse strain.

This case report found that dupilumab treatment in a 5-year-old with prurigo nodularis considerably reduced her itch severity and nearly cleared the skin lesions after six months.

CTP-543 significantly improved eyebrow and eyelash regrowth and patient satisfaction in adults with alopecia areata.

In this cross-sectional study, researchers found no significant difference in effectiveness between paclitaxel-carboplatin and pemetrexed-carboplatin for treating pulmonary adenocarcinoma with negative EGFR mutations, but paclitaxel-carboplatin was more cost-effective and associated with more frequent severe haematological toxicities.

This study described four adult male cases of Kennedy disease with typical neurological symptoms and noted gynecomastia as the most frequent endocrinological manifestation, accompanied by an abnormal expansion in the androgen receptor gene.

In this placebo-controlled study, finasteride significantly improved symptoms, reduced prostate size, and increased urine flow rate in patients with moderately symptomatic BPH over two years.

This case report documents acquired progressive kinking of the hair in a prepubertal boy but does not provide new clinical results.

This article discusses Human Metapneumovirus (HMPV) and highlights the need for continued research, noting that while supportive treatments exist, no vaccines or specific therapies are currently available.

This research discusses Stevens-Johnson syndrome and toxic epidermal necrolysis, life-threatening conditions often induced by immune-mediated drug reactions. Optimal management involves early diagnosis, drug withdrawal, and supportive therapy, though evidence for systemic treatments like corticosteroids and cyclosporin remains variable and lacks randomized controlled trial confirmation.

This study found that inhibiting DPP4 during a critical period post-wounding increases hair follicle regeneration and Wnt signaling in large skin wounds.

This study reported that mice on a phenylalanine-deficient diet showed symptoms such as weight loss, gastric dilation, and thymic depletion, which echo human phenylalanine deficiency manifestations.

This study found that photodynamic therapy may offer a new option for removing nonpigmented hair, although it was less effective than diode laser for black hair in mice.

This review provides an in-depth analysis of the structure and function of c-kit activation, and its role in both normal physiological and pathological conditions, with no new research findings reported.

This study found that a community education program using group discussions and leaflets significantly increased knowledge and skills among Sungai Bilu residents in South Kalimantan for using riverbank plants as alternative medicine.

This study found that BMP2 increased PTEN expression and induced autophagy, promoting hair follicle stem cell differentiation in both in vitro models and a mouse wound model.

This study found that activating PKM2 and Wnt/β-catenin signaling enhanced hair regrowth and hair follicle stem cell proliferation in mice, suggesting a potential alopecia treatment strategy.