July 2021 in “PARIPEX INDIAN JOURNAL OF RESEARCH” This study highlighted knuckle hyperpigmentation as an early sign of vitamin B12 deficiency, indicating a potential link to megaloblastic anemia in the vegetarian population in India.
December 2021 in “Figshare” This study found that BBS7 is crucial for maintaining Shh signaling and periodontal ligament homeostasis, with occlusal hypofunction leading to its downregulation and impacting cell migration and angiogenesis.
January 2005 in “Australian viticulture” This study found that different bovine epithelial tissues express varying types of cytokeratins, with hair follicle and nasolabial gland expressing both acidic and basic types, while others express only one or the other.
10 citations
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November 2017 in “Journal of Investigative Dermatology” In this study, researchers identified a novel homozygous variant in the FAM83G gene responsible for autosomal recessively inherited palmoplantar keratoderma with curly hair in a consanguineous Pakistani family, suggesting FAM83G plays a crucial role in skin and hair homeostasis.
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14 citations
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March 2014 in “Journal of the Society of Cosmetic Scientists of Korea” This study suggests that ethanol extracts from ten selected Korean herb medicines reduced inflammatory markers in a cell model and did not cause skin irritation in human testing, indicating potential cosmetic use for irritation prevention.
This study mapped the curly mutation in mice to a specific region on chromosome 11, identifying it as a candidate model for studying human genetic hair disorders.
1 citations
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August 2014 in “OhioLink ETD Center (Ohio Library and Information Network)” This research provides insights into how keratin hydrogels, modified to control disulfide crosslinking, may function as a treatment platform for bone injuries.
October 2025 in “Journal of Neurophysiology” In this study, researchers identified two types of potassium channels, BK and Kv4.2, in rat Merkel cells and reported that these channels play important roles in repolarizing action potentials and maintaining resting membrane potentials, potentially influencing tactile encoding in these cells.
July 2024 in “Journal of Investigative Dermatology” Recombinant human TSG-6 speeds up wound healing in diabetic mice.
September 2024 in “Journal of the American Academy of Dermatology” In this study, DataDerm revealed that from 2016 to 2022, a majority of patients diagnosed with keratinocyte carcinoma were male, predominantly white, and commonly between 56-75 years old, with most living in urban areas and having a history of non-melanoma skin cancer.
December 2021 in “Figshare” This study found that downregulation of BBS7 in periodontal ligament cells was associated with reduced Sonic hedgehog signaling, which plays a crucial role in maintaining PDL homeostasis.
June 2023 in “British Journal of Dermatology” This pilot study found that night shift workers showed fewer signs of wrinkle formation compared to day workers, but there were no significant differences in DNA amplification or collagen percentage.
In this study, six-week-old male mice showed significantly increased hair regrowth rates and higher expression of hair growth-related factors when treated for 22 days with Lactobacillus strains and fermented Korean berry, suggesting these could be potential promoters of hair growth via gut microbiome regulation.
9 citations
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April 1999 in “Mammalian Genome” This study reports that the acidic and basic keratin gene clusters in dogs are located on chromosomes CFA9 and CFA27, respectively, similar to genetic arrangements in humans and mice.
4 citations
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January 2004 in “Biological and Pharmaceutical Bulletin” In this study, AgK114 was found to be transiently induced in hamster epidermal keratinocytes following skin damage, suggesting its role in the recovery process after injury.
June 2024 in “Okayama University Scientific Achievement Repository (Okayama University)” In this study, methanol extracts from Thai-colored rice fermented with Aspergillus molds exhibited an increase in polyphenolic content and antioxidant activity, outperforming Thai white and Japanese white rice, notably transforming key polyphenols like quercetin and ferulic acid.
1 citations
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October 2015 in “추계총회 및 학술대회” The extract promotes hair growth and may help treat hair loss.
November 2022 in “Journal of Investigative Dermatology” 118 citations
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January 2013 in “Biomaterials” This study characterized keratin-based biomaterials that self-assemble into hydrogels, demonstrating their potential to achieve hemostasis in a lethal liver injury model through specific biomaterial-receptor interactions.
16 citations
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March 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers observed that a noncanonical mechanism involving the γ-secretase-dependent, RBPj-independent Notch intracellular domain improves survival in Msx2-Cre mice by delaying hair follicle destruction and reducing disease severity.
31 citations
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October 1992 in “PubMed” This study demonstrated immunological cross-reactivity between mycobacterial heat-shock protein 65 and human epidermal cytokeratin 1/2, suggesting that this cross-reactive epitope might play a role in skin diseases.
23 citations
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January 2017 in “Journal of Oleo Science” This review discusses the use of supercritical carbon dioxide for extracting rice bran oil, noting its advantages over conventional methods for preserving nutrients and antioxidants, but provides no new experimental results.
December 2021 in “Figshare” This study found that BBS7 downregulation in occlusal hypofunctional PDL affects Sonic hedgehog signaling activity, impacting PDL homeostasis.
This study in Gansu alpine fine-wool sheep identified two SNPs in the KRT71 gene that significantly affect wool length, with distinct expression patterns observed in hair follicles, suggesting KRT71 as a candidate gene for enhancing wool production traits.
66 citations
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February 2013 in “PeerJ” This study found that CB1 activation by a specific agonist led to decreased expression of keratins K6 and K16 in human skin and inhibited keratinocyte proliferation, suggesting potential for cannabinoid receptors in psoriasis management.
86 citations
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May 2002 in “Journal of Investigative Dermatology” This study characterized a new human keratin, hK6irs1, specifically found in the inner root sheath of hair follicles, which suggests its role in the structural integrity and guidance of growing hair shafts.
30 citations
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October 1999 in “Differentiation” This study found that expression of certain mutant keratin genes in mice led to severe alopecia, suggesting a similar mechanism could cause hair loss in humans.
9 citations
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January 2020 in “IEEE Access” This study reports that a robotic and AI-based system successfully analyzes FUE hair transplant procedures, aiding surgeons in planning and assessing operation success through detailed pre-op and post-op evaluations.
June 2024 in “International journal of biological macromolecules” This study reports that beta-glucan hybrid hydrogels, reinforced with laponite nanoclay, showed promising results in rat models for managing hemorrhage and diabetic wound healing by enhancing hemostasis, reducing inflammation, and promoting faster wound closure and tissue regeneration.