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This study found that cutaneous stem cells in the basal layer of fetal human skin contribute to the development of the epidermis and hair follicles, with specific marker expressions during different stages of skin development.

This study found that the repressive histone mark H2AK119ub links inhibitory FGF signals with the quiescent state in hair follicle stem cells, revealing a signaling-epigenetic axis crucial for maintaining stem cell quiescence and tissue homeostasis.

This study found that mouse hair follicle stem cells in a quiescent state exhibit greater chromatin dynamics and de-differentiation potential, suggesting higher cell fate plasticity compared to their proliferative or differentiated counterparts.

Keratin patterns in hair follicles help understand hair growth and potential hair and nail disorders.

In this study, researchers explored the heterogeneity of pigment cells in the human scalp anagen hair follicle bulb and discovered unexpected subpopulations of melanocytes, including immature SOX10-negative cells, highlighting potential non-melanogenic roles or transitional migratory functions that require further investigation.

This review discusses the complexity and genetic organization of human keratin gene clusters and addresses the ongoing need for an updated unified naming system; it reports no new clinical results.

In this study, researchers identified KRT6A as a potentially important gene in mesenchymal stem cell-derived treatments for alopecia areata, revealing its role as a diagnostic marker, predictor of disease severity, and a protective factor, with overexpression alleviating hair loss in experimental models.

This study identified a comprehensive global landscape of stemness-related gene clusters in adipose-derived mesenchymal stem cells, revealing that stemness was highest in cells from young donors and lowest in those from elderly donors.

This study found that K6a expression in mouse sebaceous gland ducts correlates with Hedgehog signaling, suggesting a role in duct fate.

This study found that K79+ keratinocytes migrate outward to help form the hair follicle lumen both during development and adult regeneration, revealing a novel mechanism of hair follicle formation in mice.

This study suggests that Artemis, particularly phosphorylated at serine 516, may have roles in hair follicle growth by influencing differentiation, proliferation, apoptosis, and cell cycling.

This study demonstrated that hair follicle bulge stem cells can form epidermis in a tissue-engineered skin model, highlighting the significance of K5/K17 filaments in slow-cycling stem cell subsets.

In this study, AgK114 was found to be transiently induced in hamster epidermal keratinocytes following skin damage, suggesting its role in the recovery process after injury.

This study investigated the roles of long non-coding RNAs in mouse hair follicle stem cells, using sequencing to identify potential biomarkers and targets for treatments in both mice and humans.

Krox20 is crucial for hair growth and maintaining skin stem cells.

This study found that topical treatment with 7DHC and BM15766 reduced hair growth in mice compared to those treated with Ethanol/DMSO, and hair did not recover after treatment ceased, alongside increased apoptotic cells and decreased expression of specific genes.

This study found that keratin 15 expression in trichoepitheliomas and some basal cell carcinomas suggests a link to hair follicle stem cells in the bulge.

This study identified a novel KRT86 mutation associated with autosomal dominant monilethrix, expanding understanding of its genetic basis beyond known motifs.

This study identified hair shaft progenitors in the matrix that regulate hair growth and pigmentation by creating a niche dependent on stem cell factor, implicating KROX20+ cells in these processes.

This study found that the RNA helicase DDX6 is essential for maintaining self-renewal in epidermal progenitor cells by promoting the translation of proliferation regulators and degrading differentiation-inducing mRNAs.

This study found that the absence of Hes1 in hair follicles delays secondary hair germ activation and shortens the anagen phase, impacting HFSC self-renewal and long-term hair regeneration.

This study found that the creation of hair follicle lumens in mice is driven by the outward migration of keratin 79-positive cells, suggesting a novel mechanism for generating hollow cores in hair follicles.

This study found that Dab2 conditional knockout mice experienced delayed hair follicle cycles and reduced hair follicle stem cell activity, suggesting Dab2's crucial role in regulating stem cell activation and anti-aging process in hair follicles.

This study examined the expression patterns of various cytokeratins in the outer root sheath of human anagen hair follicles, noting distinct differentiation patterns and localization of keratin markers.

In this study, the researchers reported that Krox20 plays a crucial role in epidermal homeostasis and hair development, influencing stem cell maintenance and cell survival through the modulation of cellular pathways.

Keratin 79 cells help form and regenerate hair canals.

A common mutation in the hHb6 gene is linked to monilethrix, but other factors may also play a role.

A specific gene mutation causes severe skin and nail issues and hair loss.

This study describes a method for labeling and tracking hair follicle stem cells in mouse skin using a Cre/lox recombination system with tamoxifen, providing insights into stem cell behavior and contribution to tissue regeneration.