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The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

The X5 Hairlaser might help treat male hair loss, but more research is needed.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The polyherbal hair gel is effective against fungal infections and helps nourish hair and prevent graying.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Nanotechnology shows promise for better chronic wound healing but needs more research.

Skin doctors should recognize and treat conditions like hair-pulling and skin-picking early, often using therapy and medication, to help 50-70% of patients.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Eating certain seeds may help reduce symptoms of Polycystic Ovary Syndrome.

Some drugs can cause hair loss, and stopping these drugs often leads to hair regrowth.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

Tamoxifen caused hair loss in a 52-year-old woman.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Ginsenoside Rb1 from Panax ginseng helps mink hair grow by activating certain cell signals.

The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

Natural products may help treat skin inflammation from abnormal adrenal hormones.

Laser treatment and deroofing are effective options for hidradenitis suppurativa.

Gilles de la Tourette syndrome is treatable, with behavioral therapy as a recommended first option and other treatments available for more severe cases.

Southeast Asian herbs show promise for skin and hair care, but more research is needed to confirm their effectiveness in cosmetics.

Saw palmetto is not proven to improve urinary flow, prostate size, or hair loss.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.

Microemulsions could improve how drugs are delivered and absorbed in the body.

ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.

Anti-glycation treatments might slow skin aging, but more research is needed.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.