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AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

The document concludes that oral finasteride and topical minoxidil are effective for genetic hair loss, while other treatments for different types of hair loss show promise but need more research.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

Androgens can both increase body hair and cause scalp hair loss.

Early treatment of fibrosing alopecia in a pattern distribution may improve outcomes.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

Heredity and hormones cause common hair loss, and topical minoxidil is the first recommended treatment.

Some medications for inflammation can cause a condition with scalp rashes and hair loss, often linked to Crohn's disease, and may require treatment changes to prevent permanent hair loss.

The article concludes that understanding Frontal Fibrosing Alopecia (FFA) is crucial for effective treatment, which includes medication like 5α-reductase inhibitors and hydroxychloroquine.

Finasteride reduces the need for prostate surgery but may increase the risk of depression and persistent sexual side effects.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Larger prostate size in older men may be linked to poorer semen quality and fertility issues.

Intralesional corticosteroids and 5-alpha-reductase inhibitors are the best treatments for frontal fibrosing alopecia.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.

Hair loss drugs may cause sexual issues and infertility in men.

Early diagnosis and combination therapy, especially with finasteride and dutasteride, are key to managing Frontal Fibrosing Alopecia effectively.

Long-term medication for enlarged prostate might not clearly affect the timing or outcomes of later surgery.

A compound from Calophyllum inophyllum L. leaf may help treat non-small cell lung cancer.

Formestane is a preferred second-line treatment for advanced breast cancer in postmenopausal women because it's effective and has fewer side effects.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Effective, well-tolerated, and affordable treatments are needed for recurrent ischemic priapism.

A man lost all his hair after stopping hepatitis C treatment and it didn't grow back.

Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

Finasteride effectively blocks enzyme causing male pattern baldness.

Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.