76 citations
,
July 2019 in “Scientific Reports” This study found that baicalin delivery through polymeric nanocapsules significantly enhanced its anticancer activity in breast cancer cell lines MCF-7 and MDA-MB-231.
68 citations
,
March 2019 in “Advanced Healthcare Materials” This review assesses the benefits and limitations of various supramolecular hydrogels, including polymeric and peptide-based types, for wound healing, but reports no new clinical results.
67 citations
,
June 2018 in “Engineering in Life Sciences” This review discusses advancements in plant cell culture technology for producing potent natural cosmetic ingredients and reports no new experimental results.
67 citations
,
April 2007 in “Journal der Deutschen Dermatologischen Gesellschaft” This article reviews the development and formulation of shampoos, emphasizing their dual role as cosmetic and medicinal products, but presents no new experimental findings.
66 citations
,
February 2010 in “CrystEngComm” Made 8 minoxidil samples; 1 cocrystal, 7 salts formed.
56 citations
,
January 2007 in “Pharmaceutical Development and Technology” This study found that finasteride-loaded liposomal formulations achieved significantly higher skin permeation and deposition compared to conventional gels and solutions, suggesting potential for effective topical application.
53 citations
,
January 1993 in “Biochemical Pharmacology” This study reports a method for efficiently synthesizing chromeno-pyrimidine-N-oxides in good to excellent yields, confirmed by X-ray analysis, through a reaction between 4-chloro-3-formylcoumarin and aromatic carboximide oximes.
48 citations
,
January 2017 in “Skin Pharmacology and Physiology” This study found that polymeric nanoparticles may effectively deliver finasteride topically to hair follicles, potentially improving alopecia treatment with fewer side effects than oral forms.
48 citations
,
December 2013 in “Drug Delivery and Translational Research” This study found that minoxidil-loaded niosomes with a Span 60 and cholesterol ratio of 1:2 significantly increased skin retention of minoxidil compared to control gel.
44 citations
,
January 2010 in “International journal of trichology” This article discusses the complexity of selecting hair cleansing products and conditioners and reports no new scientific findings or results.
39 citations
,
April 2019 in “Journal of Biomaterials Science, Polymer Edition” This review discusses recent research and applications of RADA16 and RADA16-based peptide scaffolds in biomedicine, including their roles in tissue repair and drug delivery, but reports no new clinical results.
36 citations
,
August 2021 in “Nature Cell Biology” This review discusses the potential of organoids in modeling COVID-19 disease and developing therapies, without reporting new results, and highlights opportunities and challenges in their application for research.
35 citations
,
August 2010 in “The American journal of pathology” This study reports that hypomorphic alleles of the Ass1 gene in mice resemble human CTLN1, providing a potential model for preclinical studies and indicating that standard treatments for CTLN1 can rescue phenotypes.
34 citations
,
October 2021 in “Scientific Reports” This study found that nobiletin-loaded vesicles effectively restored skin condition in a mouse model of skin cancer, suggesting they are a promising treatment delivery system.
34 citations
,
December 2012 in “Indian Journal of Dermatology, Venereology and Leprology” Mesotherapy shows promise for cellulite and facial rejuvenation but has mixed results for body sculpting and hair loss, with more research needed for safety and effectiveness.
32 citations
,
November 2020 in “Nanomaterials” This study found that excipients significantly influence the effectiveness of curcumin nanocrystals in dermal applications, enhancing or hindering hair follicle targeting and passive diffusion based on their selection.
30 citations
,
April 2017 in “Journal of structural biology” This study suggests that human keratin fiber matrix has a well-defined nano-scale grainy structure rather than being amorphous, with grain size influenced by chemical treatments, temperature, humidity, and follicle-level factors.
28 citations
,
December 2010 in “Langmuir” Hair fibers interact through classical forces, which are influenced by treatments and products, important for hair care and other applications.
27 citations
,
January 1984 in “Pharmacology & Therapeutics” This review discusses androgen manipulation strategies for conditions like benign prostatic hyperplasia and prostatic carcinoma but reports no new clinical results.
24 citations
,
July 2022 in “Journal of Applied Pharmaceutical Science” This review discusses the aesthetic and dermatological uses of exogenous hyaluronic acid for skin rejuvenation and highlights the need for thorough investigation to confirm its claimed benefits, but it reports no new clinical findings.
23 citations
,
January 2022 in “Biomaterials Science” Non-viral vectors show promise for safe and effective CRISPR/Cas9 gene editing in treating diseases.
22 citations
,
October 2019 in “International Journal of Nanomedicine” This study suggests that the hydrogel nanoparticle formulation of hair growth-promoting compounds may enhance hair follicle penetration and induce hair growth in tested models, demonstrating its potential as a hair growth treatment.
21 citations
,
July 2017 in “Journal of Cosmetic and Laser Therapy” This review discusses the research and development of vesicular carriers to enhance the delivery and effectiveness of active ingredients in cosmetic products, reporting no new clinical results.
19 citations
,
July 2020 in “Journal of drug delivery science and technology” This study found that nano-sized minoxidil formulations significantly increased skin penetration and follicular drug delivery for alopecia areata treatment, compared to conventional ethanol-based solutions, and demonstrated effective controlled release over six hours.
19 citations
,
January 2000 in “Biological and Pharmaceutical Bulletin” In this study, the researchers observed that the transdermal permeation mechanisms of diclofenac salts differ based on counterions, with varying pathways and routes for passive and iontophoretic transport.
17 citations
,
April 2017 in “International Journal of Biological Macromolecules” This study found that alginate beads containing monoolein demonstrated promising potential for managing wet wounds by better absorbing excess exudate and delivering adenosine locally, favoring drug localization in damaged porcine skin compared to an aqueous solution without affecting skin viability.
16 citations
,
July 2020 in “Advanced functional materials” This review discusses the development and application of cell-derived matrices in regenerative medicine and disease modeling, presenting various fabrication techniques and future perspectives, but reports no new results.
15 citations
,
October 2016 in “Journal of dermatological treatment” This paper reviews the literature on acquired trichorrhexis nodosa, a clinical hair loss diagnosis associated with hair care practices, particularly in those with tightly curled hair, and emphasizes management through protective hair care regimens rather than traditional prescription therapies.
15 citations
,
March 2014 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” This review discusses the role of acyl-CoA binding protein (ACBP) in the epidermal barrier, noting that its disruption in mice is linked to skin and fur abnormalities; it reports no new clinical results.
14 citations
,
May 2005 in “Farmaco” This study developed a high performance capillary electrophoresis method, validated for both legal and illicit minoxidil-based products, to confirm minoxidil's presence alongside known impurities.