27 citations,
April 1992 in “Biochemical Journal” Minoxidil reduces lysine hydroxylase in skin cells.
20 citations,
January 1994 in “Archives of Biochemistry and Biophysics” Minoxidil needs specific structure to block lysyl hydroxylase; exploring alternatives may keep benefits without this effect.
[object Object] 19 citations,
January 1987 in “Dermatology” Minoxidil slows down skin cell growth and may help treat scars and skin conditions.
356 citations,
December 1986 in “The journal of cell biology/The Journal of cell biology” Hair and nail cells share similar proteins, indicating a common differentiation pathway.
106 citations,
November 2014 in “Cell Stem Cell” New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.
87 citations,
July 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.
66 citations,
January 2001 in “Vitamins and hormones” Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.
45 citations,
December 2006 in “Biopolymers” Permanent waving weakens hair by altering its protein structure.
40 citations,
January 2016 in “Elsevier eBooks” The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
38 citations,
June 2005 in “Matrix Biology” Minoxidil affects collagen-related genes, potentially helping treat fibrosis.
24 citations,
October 2017 in “Biomolecules” Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
[object Object] 22 citations,
December 2016 in “PloS one” A specific protein in chicken embryos links early skin layers to feather development.
17 citations,
July 2018 in “International Journal of Cosmetic Science” Keratin-based particles safely improve hair strength, smoothness, and heat protection.
16 citations,
September 2018 in “Journal of Molecular Liquids” The PS-b-PAA copolymer nanomicelles are effective for delivering a cancer treatment drug in photodynamic therapy.
13 citations,
July 2017 in “Biopolymers” Recombinant keratins can form useful structures for medical applications, overcoming natural keratin limitations.
12 citations,
January 2014 in “Cell structure and function” Different combinations of human hair keratins affect how hair fibers form.
11 citations,
August 2011 in “Journal of Inclusion Phenomena and Macrocyclic Chemistry” Finasteride's solubility and bioavailability improved by forming solid dispersions and inclusion complexes.
11 citations,
May 2011 in “World Journal of Pediatrics” The document emphasizes the importance of correctly identifying and classifying genetic hair disorders to help diagnose related health conditions.
10 citations,
April 2010 in “Dermatologic Surgery” Small changes in hair restoration surgery, like using special stitches and careful graft placement, can improve results and teamwork.
9 citations,
June 2020 in “Actas Dermo-Sifiliográficas” Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.
6 citations,
October 2022 in “Journal of cell science” Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.
1 citations,
July 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Keratin gene expression helps understand different types of skin cells and their development, and should be used carefully as biological markers.
1 citations,
June 2019 in “International Journal of Applied Pharmaceutics” Nanostructured lipid carriers can effectively repair hair split-ends for over 3 days.
1 citations,
April 2016 in “CRC Press eBooks” Skin aging reflects overall body aging and can indicate internal health conditions.
1 citations,
October 1984 in “Clinics in dermatology” People distressed by minor skin changes should consult dermatologists with cosmetic expertise, and a public Cosmetic Dermatology Service with mental health support is recommended.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Removing Sprouty genes in mice causes various hormone-related issues but does not increase cancer risk by one year of age.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Scientists made a mouse that shows how a specific protein in the skin changes and affects hair growth and shape.
August 2022 in “Frontiers in genetics” A new genetic change in the DSC3 gene is linked to a rare condition causing hair loss and skin blisters in a child.
January 2017 in “Clinical approaches and procedures in cosmetic dermatology” Anti-glycation treatments might slow skin aging, but more research is needed.
Accurate diagnosis of cicatricial alopecias requires thorough scalp examination and multiple biopsy techniques.