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Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.

Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

Losing weight and eating better are key to managing metabolic syndrome and its related conditions.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

SHBG may be a useful early indicator and treatment target for PCOS.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

SLICK cattle have better heat tolerance due to specific gene expression and pathway differences.

Inducing ferroptosis in hepatic stellate cells is crucial for treating liver fibrosis.

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

The document concludes that managing Dunnigan-Type Familial Partial Lipodystrophy involves treating associated health issues and using medications like metformin and leptin replacement.

Women with PCOS and higher androgen levels are more likely to have fatty liver disease.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.

Women with PCOS are more likely to have fatty liver disease, especially if they have metabolic problems.

Many young Egyptian women with PCOS also have fatty liver disease, especially if they are overweight and insulin resistant.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

Some chemicals absorbed through the skin can cause serious health problems.

Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.