Pruritic Urticarial Papules and Plaques of Pregnancy

    G. Barrenetxea, Juan Carlos Melchor, M.J. Barbazán, Gerardo Aranguren, F.J. Rodríguez-Escudero
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    TLDR The skin condition PUPP usually gets better on its own after giving birth and is unlikely to happen again in future pregnancies.
    The document described a case of pruritic urticarial papules and plaques of pregnancy (PUPP) in a 25-year-old pregnant woman, which resolved spontaneously two days after childbirth. The patient was treated with topical corticosteroids and systemic antihistamines. The paper highlighted the distinction between PUPP and other pregnancy dermatoses, such as herpes gestationis (HG), emphasizing that PUPP typically resolves postpartum without treatment. A skin biopsy and direct immunofluorescence testing were conducted, showing C1q deposits but no immunoglobulins or C3, supporting the diagnosis of PUPP. The authors concluded that PUPP is a distinct clinical entity with a positive prognosis and low recurrence risk in future pregnancies.
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