research Keratins in Health and Cancer: More Than Mere Epithelial Cell Markers
Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.
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60-90 / 1000+ results research Intermolecular Disulfide Cross-Linked Structural Change Induced by Permanent Wave Treatment of Human Hair with Thioglycolic Acid
Permanent wave treatment with thioglycolic acid changes hair structure by altering disulfide bonds.
research The cDNA-Deduced Amino Acid Sequence for Trichohyalin, a Differentiation Marker in the Hair Follicle, Contains a 23 Amino Acid Repeat
Trichohyalin, a hair follicle protein, has a part with repeating patterns of 23 amino acids.
research The Secrets of Beautiful Hair: Why Is It Flexible and Elastic?
Beautiful hair is flexible and elastic due to its unique double-layered structure and can be enhanced with succinic acid treatment.
research Hair Keratin Associated Proteins: Characterization of a Second High Sulfur KAP Gene Domain on Human Chromosome 21 in Fond Memory of Dr. Peter Steinert
A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.
research Structure of Intermediate Filament Assembly in Hair Deduced from Hydration Studies Using Small-Angle Neutron Scattering
Hair's internal fibers are arranged in a pattern that doesn't let much water in, and treatments like oils and heat change how much water hair can absorb.
research Differential Expression of Proteins Associated with the Hair Follicle Cycle: Proteomics and Bioinformatics Analyses
Researchers found 44 proteins that change during different hair growth stages and may be important for hair follicle function.
research Identification of the Key Proteins Associated With Different Hair Types in Sheep and Goats
Different proteins are linked to the varying thickness of sheep and goat hair types.
research Label-Free Proteomics to Identify Keratins and Keratin-Associated Proteins and Their Effects on the Fleece Traits of Inner Mongolia Cashmere Goats
Proteins influence the quality and traits of cashmere goat fleece, affecting hair strength and diameter.
research Downregulation of mRNAs Encoding Keratin-Associated Proteins in the Tongue of Mice Fed a High-Fat Diet
A high-fat diet may weaken tongue structure by reducing certain protein genes.
research Ancient Lineages of the Keratin-Associated Protein (KRTAP) Genes and Their Co-option in the Evolution of the Hair Follicle
Keratin-associated proteins have ancient origins and were used for different purposes before being adapted for hair in mammals.
research Cortical Cell Types and Intermediate Filament Arrangements Correlate with Fiber Curvature in Japanese Human Hair
Hair curvature in Japanese people is linked to specific cell types and filament arrangements in the hair cortex.
research Proteomic Tools for the Investigation of Human Hair Structural Proteins and Evidence of Weakness Sites on Hair Keratin Coil Segments
Hair proteins have weak spots in their α-helical segments.
research Molecular Modeling and Structural Characterization of a High Glycine–Tyrosine Hair Keratin Associated Protein
The 3D structure of a key hair protein was modeled, revealing specific helical structures and stabilization features.
research Mutations in the Helix Termination Motif of Mouse Type I IRS Keratin Genes Impair the Assembly of Keratin Intermediate Filament
Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.
research Polymorphisms in the Human High Sulfur Hair Keratin-Associated Protein 1, KAP1, Gene Family
Genetic variations in hair keratin proteins exist but don't significantly affect hair structure.
research The Expanding Significance of Keratin Intermediate Filaments in Normal and Diseased Epithelia
Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.
research Evolution of Hard Proteins in the Sauropsid Integument in Relation to the Cornification of Skin Derivatives in Amniotes
Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.
research An Integrated Analysis of Cashmere Fineness lncRNAs in Cashmere Goats
lncRNA XLOC_008679 and gene KRT35 affect cashmere fineness in goats.
research The Structure of the Amorphous Matrix of Keratins
Human hair keratin fibers have a detailed nano-scale structure that changes with different conditions.
research Long Noncoding RNA and Gene Expression Analysis of Melatonin-Exposed Liaoning Cashmere Goat Fibroblasts Indicating Cashmere Growth
Melatonin treatment increases a specific RNA in goat cells that boosts cashmere growth.
research Ancient Lineages of the Keratin-Associated Protein (KRTAP) Genes and Their Co-Option in the Evolution of the Hair Follicle
Some hair protein genes evolved early and were adapted for use in hair follicles.
research Biocompatibility Of Kaps-Depleted Residual Hair
KAP-depleted hair causes less immune response and is more biocompatible for implants.
research Alopecia Areata Susceptibility Variant Identified by MHC Risk Haplotype Sequencing Reproduces Symptomatic Patched Hair Loss in Mice
A gene variant causes patched hair loss in mice, similar to alopecia areata in humans.
research In This Issue
Advancements in hair biology include new treatments and tools for hair growth and alopecia.
research Genetics of Structural Hair Disorders
The document concludes that over 500 genes are linked to hair disorders and this knowledge is important for creating new treatments.
research Transcriptome Analysis Reveals the Genetic Basis Underlying the Development of Skin Appendages and Immunity in Hedgehog (Atelerix Albiventris)
Genes related to keratin, skin cell differentiation, and immune functions are key in hedgehog skin and spine development.
research Transcriptome Analysis Reveals the Genetic Basis Underlying the Development of Skin Appendages and Immunity in Hedgehog (Atelerix Albiventris)
The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.
research Responses of Type II Spiral Ganglion Neurites to Stripes of Laminin and Fibronectin
Type II spiral ganglion neurites avoid high concentrations of laminin and fibronectin.
research How Different Is Human Hair? A Critical Appraisal of Global Hair Fibre Characteristics and Properties Towards Defining a More Relevant Framework for Hair Type Classification
Human hair varies widely and should be classified by curl type rather than race.