research A Volar Skin Excisional Wound Model for In Situ Evaluation of Multiple-Appendage Regeneration and Innervation
The study concluded that the new wound model can be used to evaluate skin regeneration and nerve growth.
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research Proceedings of the Ninth World Congress for Hair Research 2015
The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
research Intermediate Filaments: Regulation of Gene Expression and Assembly
Intermediate filaments are crucial for cell structure and function, regulated by specific genes and proteins.
research Epidermolysis Bullosa Simplex Caused by Distal Truncation of BPAG1-e: An Intermediate Generalized Phenotype with Prurigo Papules
The study described a case of epidermolysis bullosa simplex (EBS) in a 39-year-old Syrian man, caused by a rare homozygous nonsense mutation in the DST gene, leading to a truncated BPAG1-e protein. This mutation resulted in an intermediate generalized phenotype with skin fragility, blistering, and prurigo papules, but did not affect hair, nails, or mucous membranes. Immunofluorescence and immunoblot analyses showed reduced expression and truncation of BPAG1-e, impairing its binding to intermediate filaments. The mutation might have led to increased expression of plectin and contributed to pruritus through up-regulation of proinflammatory cytokines. This case highlighted a novel phenotype linked to DST mutations, underscoring BPAG1-e's role in skin integrity and pruritus.
research Hair: The Most Sophisticated Biological Composite Material
Hair is a complex protein fiber with unique properties useful for developing hair products.
research The Physical and Chemical Disruption of Human Hair After Bleaching – Studies by Transmission Electron Microscopy and Redox Proteomics
Bleaching hair causes severe structural and chemical damage, including protein loss and oxidation.
research Isolation and Characterization of a Novel Hair Follicle-Specific Gene, Hacl-1
Researchers found a new gene, hacl-1, that is active in mouse hair follicles during hair growth and may be important for hair biology.
research Characteristic Microstructure of Curved Human Hair
Curved human hair has different structures on its convex and concave sides.
research Water Distribution in Human Hair Microstructure Elucidated by Spin Contrast Variation Small-Angle Neutron Scattering
The technique showed that human hair has two main parts, with 68% being rigid and the rest flexible, and water swelling affects its structure.
research Structural Analysis of Curly and Straight Human Hair Fibers by Scanning Microbeam SAXS
Curly and straight hair differ in how their internal fibers are arranged.
research Trichohyalin Mechanically Strengthens the Hair Follicle
Trichohyalin makes hair follicles stronger.
research In Vitro Analysis of Hemostatic Efficacy of Fibrinogen Precipitation With Varied Keratin Fraction Compositions
Human hair proteins can help blood clot when mixed in equal parts.
research Rational Design of Keratin Nanoparticles Utilizing Diverse Hair Protein Fractions for Controlled Drug Release
Scientists made nanoparticles from human hair proteins to improve drug delivery.
research The Self-Recovery Phenomenon of Oxidized Hair
Oxidized hair can naturally regain strength and stability over six months.
research Endocrine Controls of Keratin Expression
Hormones control keratin production in skin and hair.
research Attenuated Total Reflection Fourier Transform Infrared Spectroscopy Analysis of Human Hair Fiber Structure
Human hair has different protein structures in its cuticle and cortex.
research The Epidermis: Rising to the Surface
The document concludes that recent research has improved understanding of skin diseases and the balance between cell growth and differentiation in the epidermis.
research The Biology of Hair Follicles
Hair follicle biology advancements may lead to better hair growth disorder treatments.
research The Proximal Promoter of the Human Transglutaminase 3 Gene
The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.
research Hair Growth Promoting Effects of Adipose Tissue-Derived Stem Cells
Fat tissue stem cells may help increase hair growth.
research Ultrastructural Evaluation of the Radioprotective Effects of Melatonin Against X-Ray-Induced Skin Damage in Albino Rats
Melatonin may reduce skin damage caused by X-rays in rats.
research Identification of the Ovine Keratin-Associated Protein 22-1 (KAP22-1) Gene and Its Effect on Wool Traits
The gene KAP22-1 affects wool yield and fiber shape in sheep.
research Size Polymorphisms in the Human Ultrahigh Sulfur Hair Keratin-Associated Protein 4, KAP4, Gene Family
The study found that variations in hair protein genes are likely due to evolutionary deletions or duplications.
research An Intrinsic Oscillation of Gene Networks Inside Hair Follicle Stem Cells: An Additional Layer That Can Modulate Hair Stem Cell Activities
Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.
research Multifunctional Merkel Cells: Their Roles in Electromagnetic Reception, Fingerprint Formation, Reiki, Epigenetic Inheritance, and Hair Form
Merkel cells may have roles in sensing magnetic fields, creating fingerprints, Reiki energy healing, passing on environmental information to offspring, and influencing hair shape.
research A Highly Resistant Structure Between Cuticle and Cortex of Human Hair
A tough membrane between the outer and inner layers of human hair protects it from damage.
research Is Thyrotropin-Releasing Hormone a Novel Neuroendocrine Modulator of Keratin Expression in Human Skin?
Thyrotropin-releasing hormone may help control skin and hair growth and could aid in treating related disorders.
research Targeting the Stem Cell Niche: Role of Collagen XVII in Skin Aging and Wound Repair
Collagen XVII is important for skin aging and wound healing.
research Highly Conserved Keratin-Associated Protein 7-1 Gene in Yak, Taurine, and Zebu Cattle
The KRTAP7-1 gene is very similar across different cattle and yak breeds and likely plays a role in hair strength and shape.
research A Two-Phase Model of Skin Epidermal Stratification: Lessons from Centrosomes
Removing centrosomes from skin cells leads to thinner skin and stops hair growth, but does not greatly affect skin cell differentiation.