research Association Between Interleukin 18 Polymorphisms and Alopecia Areata in Koreans
Certain genetic variations in IL18 may increase the risk of alopecia areata in Koreans.
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research p53 Is a Direct Transcriptional Repressor of Keratin 17: Lessons from a Rat Model of Radiation Dermatitis
The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.
research Interleukin-6 from Adipose-Derived Stem Cells Promotes Tissue Repair by Increasing Cell Proliferation and Hair Follicles in Ischemia/Reperfusion-Treated Skin Flaps
IL-6 from stem cells helps repair skin and grow hair.
research Genetic Analysis of Interleukin 18 Gene Polymorphisms in Alopecia Areata
Certain IL-18 gene variations may increase the risk of alopecia areata.
research Interleukin 6 and STAT3 Regulate p63 Isoform Expression in Keratinocytes During Regeneration
The conclusion is that the IL-6/STAT3 activation affects p63 expression in healing wounds, which may help in hair follicle regeneration.
research Wound Healing Protects Against Chemotherapy-Induced Alopecia in Young Rats via Up-Regulating Interleukin-1β-Mediated Signaling
Wound healing can help prevent hair loss from chemotherapy in young rats by increasing interleukin-1β signaling.
research Platelet-Rich Plasma in the Treatment of Alopecia Areata: A Retrospective Evaluation of 17 Patients
PRP treatment may help with alopecia areata, especially in newer cases.
research Treatment of Chronic Alopecia Areata With Tildrakizumab: An Open-Label Pilot Study
Tildrakizumab showed limited effectiveness in treating chronic alopecia areata in a small group of patients.
research Successful Treatment of Palmoplantar Pustular Psoriasis with Brodalumab
Brodalumab effectively treated a man's severe hand and foot psoriasis.
research Mucosal TLR5 Activation Controls Healthspan and Longevity
Activating TLR5 in the gut can extend lifespan and improve health in aged mice.
research Tregs: Where We Are and What Comes Next?
The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.
research Probiotic Bacteria Induce a Glow of Health
Probiotic bacteria improved skin and hair health in aged mice.
research The Pathogenesis of Alopecia Areata
Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.
research COVID-19: Understanding Inter-Individual Variability and Implications for Precision Medicine
The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.
research Pitx2, A β-Catenin-Regulated Transcription Factor, Regulates The Differentiation Of Outer Root Sheath Cells Cultured In Vitro
Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.
research An Update on Medical Treatment Options for Hidradenitis Suppurativa
New treatments for a chronic skin condition show promise, but individualized plans are crucial due to varying responses.
research Review of Scalp Alopecia Due to a Clinically Unapparent or Minimally Apparent Neoplasm (SACUMAN)
SACUMAN, a rare condition causing hair loss without clear signs, is often misdiagnosed and needs scalp biopsies for accurate detection.
research Emerging Therapies for Acne Vulgaris
New acne treatments show promise as alternatives to traditional therapies.
research Double-Stranded RNA Induces Inflammation via the NF-κB Pathway and Inflammasome Activation in the Outer Root Sheath Cells of Hair Follicles
Double-stranded RNA causes inflammation in hair follicle cells, which may help understand and treat alopecia areata.
research Overexpression of IL-18 in the Proliferative Phase Endometrium of Patients With Polycystic Ovary Syndrome
Women with PCOS, especially those overweight, have higher levels of IL-18 in their endometrium, which may affect fertility.
research Medical Treatment of Hepatocellular Carcinoma: Any Progress?
As of 1994, treatments for liver cancer had not significantly improved patient survival.
research ADM Scaffolds Generate a Pro-Regenerative Microenvironment During Full-Thickness Cutaneous Wound Healing Through M2 Macrophage Polarization via Lamtor1
ADM scaffolds help skin heal by promoting a healing-type immune response.
research Signal Transducer and Activator of Transcription 5B Deficiency Due to a Novel Missense Mutation in the Coiled-Coil Domain
A boy's growth and immune problems were caused by a new mutation in the STAT5B gene.
research ACTH as First Line Treatment for Acute Calcium Pyrophosphate Crystal Arthritis in 14 Hospitalized Patients
ACTH may be an effective first-line treatment for acute calcium pyrophosphate crystal arthritis.
research Perforin Expression by Cutaneous Gamma Delta T Cells
Gamma delta T cells in the skin help with healing and defense but can also cause autoimmune issues, and more research is needed to understand how they are activated.
research Prevention of Alopecia in Medical and Interventional Chemotherapy Patients
Cold caps and certain drugs may help prevent or reduce hair loss from chemotherapy, but more research is needed.
research IL-36α Promoted Wound-Induced Hair Follicle Neogenesis via Hair Follicle Stem/Progenitor Cell Proliferation
IL-36α helps grow new hair follicles and speeds up wound healing.
research Essential Role of STAT3 Signaling in Hair Follicle Homeostasis
STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.
research Hair-Cycle Changes in Two Patients Taking Tocilizumab
Tocilizumab treatment was associated with significant hair regrowth in one patient and temporary hair loss followed by regrowth in another.
research Photoprotective and Immunoregulatory Capacity of Ginsenoside Rg1 in Chronic Ultraviolet B-Irradiated BALB/c Mouse Skin
Ginsenoside Rg1 protects mouse skin from UVB damage and helps control inflammation.