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New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Ifidancitinib, a JAK inhibitor, effectively regrows hair in mice with alopecia by tiring out harmful T cells.

PlacMA hydrogels from human placenta are versatile and useful for cell culture and tissue engineering.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Vitamin D is important for bones, hair, blood pressure, and breast development.

Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Human hair keratins can self-assemble and support cell growth, useful for biomedical applications.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Minoxidil treatment improves heart defects in a DiGeorge syndrome model.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.

Hydrogel with M2-derived exosomes improves wound healing by slowly releasing exosomes that help reduce inflammation and promote tissue repair.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Elastin-like recombinamers show promise for better wound healing and skin regeneration.

Gene regulation could revolutionize hair color by altering pigmentation from within.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

The document concludes that hair loss in cats is caused by various factors, including allergies, mites, infections, and hormonal issues, with treatments varying accordingly.

Some skin diseases and their treatments can negatively affect male fertility.

Human hair's ability to get wet is complex and can change with treatments, damage, and environment.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.

Topical minoxidil is the best-supported treatment for female hair loss, but personalized plans are needed.

Phospholipase A2 is necessary for the correct placement of PIN proteins in plant roots, affecting root growth.