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CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Pioglitazone usually doesn't effectively treat or cure lichen planopilaris.

The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.

Low-dose finasteride may cause fertility issues, but stopping it can improve sperm quality and lead to pregnancy.

Special immune cells called Treg cells are important for maintaining and regenerating hair by activating a specific growth signal in hair stem cells.

Mice with a mutated Dsg3 gene showed severe symptoms but not the typical blistering of pemphigus vulgaris.

A 38-year-old man was diagnosed late with Kearns-Sayre syndrome after being wrongly treated for epilepsy.

Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.

PTHrP is important for bone formation and may be targeted for osteoporosis treatment and longevity therapies.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Memory regulatory T cells need IL-7, not IL-2, to stay in peripheral tissues.

Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Type 2 diabetes, bacterial scalp infections, and tight hairstyles like braids and weaves are linked to a higher risk of a scarring hair loss condition in African American women.

Exosomes from dermal papilla cells can help grow hair and might treat hair loss.

FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.

Fat tissue stem cells may help increase hair growth.

Toxic Shock Syndrome progresses quickly, often involves multiple organs, and is linked to Staphylococcus aureus toxins, with treatment options available but diagnostic challenges remaining.

The document concludes that there are no effective clinical treatments for hearing loss due to hair cell damage, but research is ongoing.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.