research Investigation of Variants of the Aromatase Gene (CYP19A1) in Female Pattern Hair Loss
No link found between aromatase gene and female hair loss.
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research Tamoxifen-Induced Female Androgenetic Alopecia in a Patient with Breast Cancer
Tamoxifen caused hair loss in a 52-year-old woman.
research Novel ALK5 Inhibitor TP0427736 Reduces TGF-β Induced Growth Inhibition in Human Outer Root Sheath Cells and Elongates Anagen Phase in Mouse Hair Follicles
TP0427736 may help treat hair loss by blocking a specific protein and promoting hair growth.
research Bioactive Compounds from the Roots of Asiasarum Heterotropoides
Two compounds from Asiasarum heterotropoides roots show potential as lung cancer treatments without harming normal cells.
research Marie Unna Hereditary Hypotrichosis: Identification of a U2HR Mutation in the Family from the Original 1925 Report
Researchers found a gene mutation responsible for a rare hair loss condition.
research Marie Unna Hereditary Hypotrichosis Caused by a Novel Mutation in the Human Hairless Transcript
A new mutation in the HR gene causes hair loss in a specific family.
research Minoxidil: Inhibition of Proliferation of Keratinocytes In Vitro
Minoxidil slows down keratinocyte growth without being toxic.
research In Vitro Selective Inhibition of Human UDP-Glucuronosyltransferase (UGT) 1A4 by Finasteride and Prediction of In Vivo Drug–Drug Interactions
Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.
research Twenty Nail Onychomadesis: An Unusual Finding in Cronkhite-Canada Syndrome
A man with Cronkhite-Canada syndrome had all 20 nails detach but improved with treatment.
research Anti-Androgenic Curcumin Analogues as Steroid 5-Alpha Reductase Inhibitors
Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.
research Analysis of Changes in MicroRNA Expression Profiles in Response to the Troxerutin-Mediated Antioxidant Effect in Human Dermal Papilla Cells
Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.
research Itraconazole in the Treatment of Acute and Recurrent Vulvovaginal Candidosis: Comparison of a 1-Day and a 3-Day Regimen
A 1-day or 3-day itraconazole treatment is effective for acute vulvovaginal candidosis, but recurrent cases may need longer treatment.
research Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors
Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.
research Marie Unna Hereditary Hypotrichosis: A Turkish Family with Loss of Eyebrows and a U2HR Mutation
A Turkish family with sparse hair and eyebrow loss has a mutation in the U2HR gene linked to Marie Unna hereditary hypotrichosis.
research Current Treatment of Benign Prostatic Hyperplasia
TURP is the best treatment for BPH, but some patients prefer medications like alpha-blockers and finasteride.
research Health Promotion Potential of Vegetables Cultivated in Northern Thailand: A Preliminary Screening of Tannin and Flavonoid Contents, 5α-Reductase Inhibition, Astringent Activity, and Antioxidant Activities
Some vegetables from Northern Thailand show promise for health benefits, including hair loss treatment and antioxidant properties.
research Effects of 1α,25-Dihydroxy-Vitamin D3 and Calcipotriol on Organotypic Cultures of Outer Root Sheath Cells: A Potential Model to Evaluate Antipsoriatic Drugs
Vitamin D compounds may help treat psoriasis by promoting skin cell differentiation.
research Successive Release of Tissue Inhibitors of Metalloproteinase-1 Through Graphene Oxide-Based Delivery System Can Promote Skin Regeneration
Graphene oxide helps deliver a skin healing agent over time, improving skin and hair follicle regeneration.
research Serum AMH Levels in the Differential Diagnosis of Hyperandrogenemic Conditions
Blood AMH levels are higher in women with PCOS than in those with other similar conditions.
research Combination of an Antiandrogen and a 5α-Reductase Inhibitor: A Further Step Towards Total Androgen Blockade?
Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.
research The Administration of Flumethasone by Three Different Routes, Its Measurement in the Plasma, and Some Effects on Wool Growth in Merino Wethers
Flumethasone causes wool shedding in Merino wethers, with recovery in about 60 days.
research The Negative Regulator CXXC5: Making WNT Look a Little Less Disheveled
CXXC5 is a protein that prevents hair growth and could be a target for hair loss treatment.
research Eccrine Duct Dilation as a Marker of Cicatricial Alopecia
Enlarged sweat gland ducts may indicate scarring hair loss.
research Adrenal Steroid Precursors Exert Potent Androgenic Action in the Hamster Sebaceous Glands of Flank Organs and Ears
Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.
research The Impact of Oxidative Stress in Androgenic Alopecia in Women
Oxidative stress plays a role in female pattern baldness, causing an imbalance between harmful and protective elements in the body.
research Screening of Euphorbiaceae Plant Extracts for Anti-5α-Reductase Activity
Phyllanthus urinaria extract may help treat hair loss by blocking a hair-related enzyme.
research Proprietary Herbal Extract Downregulates the Gene Expression of IL-1α in HaCaT Cells: Possible Implications Against Nonscarring Alopecia
A herbal extract may help treat certain types of hair loss by reducing a specific gene's activity.
research A Comparative In Vivo and In Vitro Evaluation of Hair Growth Potential of Extracts and an Isolate from Petroleum Ether Extract of Cuscuta Reflexa Roxb
Cuscuta reflexa extracts and an isolate promoted hair growth and could be natural treatments for hair loss.
research Safety and Efficacy of Transdermal Testosterone for Treatment of Hypoactive Sexual Desire Disorder
Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.
research Administration of Caesalpinia Bonduc Seed Extracts Ameliorates Testosterone-Induced Benign Prostatic Hyperplasia in Male Wistar Rats
Caesalpinia bonduc seed extracts may help treat enlarged prostate in rats.