research Polycystic Ovary Syndrome and Infertility: An Update
New treatments for PCOS are improving fertility and managing symptoms better.
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120-150 / 1000+ resultsresearch Successful Virilization of a PAIS Patient with a Missense Mutation in the Ligand-Binding Domain of the Androgen Receptor Using Combined High-Dose Testosterone and Aromatase Inhibitor
A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.
research Hyaluronic Acid-FGF2-Derived Peptide Bioconjugates for Suppression of FGFR2 and AR Simultaneously as an Acne Antagonist
The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.
research Epidermal Growth Factor Receptor Inhibitors: A Review of Cutaneous Adverse Events and Management
Skin side effects from cancer drugs targeting EGFR can affect treatment adherence but can be managed with antibiotics like tetracycline.
research Synergistic Antibacterial Activity and Wound Healing Properties of Selenium-Chitosan-Mupirocin Nanohybrid System: An In Vivo Study on Rat Diabetic Staphylococcus Aureus Wound Infection Model
The nanohybrid system significantly improved wound healing and showed strong antibacterial activity.
research New Fluorogenic Probes for Neutral and Alkaline Ceramidases
New probes were created to effectively measure specific enzymes involved in fat metabolism, which could help develop new drugs.
research Larvicidal Potential, Antimicrobial Properties and Molecular Docking Analysis of Egyptian Mint (Mentha Rotundifolia) Against Culex Pipiens L. (Diptera: Culicidae) and Midgut-Borne Staphylococcus Aureus
Egyptian Mint effectively kills mosquito larvae and inhibits certain bacteria.
research JAK Inhibitors for the Treatment of Alopecia Areata
JAK inhibitors show promise in treating moderate to severe alopecia areata.
research Limited Effectiveness of Platelet-Rich Plasma Treatment on Chronic Severe Alopecia Areata
Platelet-rich plasma treatment is not very effective for chronic severe alopecia areata.
research Novel Penile Ultrasound Technique to Explain Mechanism of Erectile Dysfunction in Young Patients Using Finasteride for Androgenic Alopecia
Ultrasound shows 96% of young men with erectile dysfunction after using finasteride have abnormal penile tissue.
research Androgens Activate Lipogenesis Through an AKT-Independent mTOR Pathway Stimulation and a Limitation of Autophagy in an Androgen-Sensitive Sebocyte Cell Line
Dihydrotestosterone (DHT) increases oil production in skin cells by activating mTOR, and mTOR inhibitors can reduce this effect.
research The Challenging Consultation: Management of Melanoma
The conclusion is that managing hair loss conditions like FFA and melanoma requires individualized approaches, considering new findings and balancing treatment benefits with potential risks.
research 66-Year-Old Female with Itchy Scalp and Hair Loss
A woman has a permanent hair loss condition treated with steroids and new medicines, but hair might not regrow.
research Activation of TRPV3 Inhibits Lipogenesis and Stimulates Production of Inflammatory Mediators in Human Sebocytes—A Putative Contributor to Dry Skin Dermatoses
Activating TRPV3 reduces skin oil production and increases inflammation, potentially causing dry skin issues.
research Molecular Identification of Keratinophilic Fungi Associated With Hair Scalp and Antifungal Activity of Green-Synthesis Zinc Oxide Nanoparticles
Green-synthesized zinc oxide nanoparticles effectively inhibit common fungi found on human scalp hair.
research Reply to Early Onset Effluvium Secondary to COVID-19 and Body-Hair Effluvium
COVID-19 can cause different types of hair loss, which may last up to 100 days, and treatments are still being explored.
research Loss of TET2 Tips the Scales Toward Tumorigenesis
Loss of TET2 increases the risk of skin and oral cancer.
research Dihydrotestosterone and the Concept of 5-Alpha-Reductase Inhibition in Human Benign Prostatic Hyperplasia
Blocking the enzyme that turns testosterone into DHT can safely and effectively treat enlarged prostate.
research Systematic Review of Newer Agents for the Management of Alopecia Areata in Adults: Janus Kinase Inhibitors, Biologics and Phosphodiesterase-4 Inhibitors
New oral treatments for adult hair loss show promise, especially JAK inhibitors, with mild side effects.
research Association of Common Medication With Prostate-Specific Antigen Level in 45-Year-Old German Men: Results of the PROBASE Trial
Some common medications like metformin, insulin, and ACE inhibitors can lower PSA levels, while statins don't, and low dose finasteride significantly reduces PSA.
research Bioactive Peptides Derived from Food Proteins Preventing Lifestyle-Related Diseases
Food-derived peptides may help prevent diseases like high blood pressure and high cholesterol, and can support the immune system.
research Introductory Chapter: Alopecia Management – An Update
Some types of hair loss can be reversed, others are permanent, and treatments vary by type.
research A Description of Alopecia Areata in European Patients Based on Real-World Survey Data: Physician-Reported Characterization of Severity and Associated Treatment Utilization
More effective treatments are needed for severe alopecia areata.
research Drug News and Therapeutic News
JAK inhibitors help treat some diseases but may increase risks of blood clots and cancer in certain patients.
research A Retrospective Review of Pediatric Alopecia Areata Cases Seen in a Tertiary Institution in Singapore
Most children with alopecia areata improved with treatment, but those with more hair loss had worse outcomes.
research Understanding the Mechanism of Repigmentation in Vitiligo
Understanding repigmentation mechanisms in vitiligo can improve treatments and patient outcomes.
research Anti-Acetylcholinesterase and Antioxidant Effects of Identified Compounds from Houttuynia Cordata
Houttuynia cordata compounds may help with anti-aging and hair loss.
research Aromatase Inhibitors Induce Male Pattern Hair Loss in Women
Aromatase inhibitors cause male pattern hair loss in women.
research Epidermal Keratinocytes Regulate Bacterial Immune Responses and Host Defense Through EGFR
EGFR inhibitors cause skin issues and hair loss by weakening skin defenses, suggesting antibiotics and targeted treatments can help.
research The PRIDE Syndrome: Dermatological Side Effects of EGFR Inhibitors
PRIDE syndrome includes skin and hair issues from cancer treatment with EGFR inhibitors.