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In this study, researchers observed that dandruff involves altered keratinocyte activity and a low-grade inflammatory response characterized by increased interleukin-17-producing T-cells and CCL17 levels, but without significant changes in immune cell populations or skin barrier lipids.

This review discusses the interplay between genetics, skin microbiome, and inflammation in inflammatory skin diseases, focusing on how these factors may predict and influence seborrheic dermatitis, but reports no new results.

This article discusses leukocytoclastic vasculitis, particularly its triggers, manifestations, and treatments, and reports no new experimental results; the authors highlight valproic acid's association with this condition.

This review discusses the role of hair follicle bacterial colonization in immune responses and the pathogenesis of alopecia but reports no new clinical results.

Aged skin heals slower due to more inflammation and disrupted cell communication.

This case report describes a 25-year-old woman with alopecia areata and nail spooning, which regressed almost completely after treatment with oral corticosteroids.

This study found that in atrophic acne scars, inflammation infiltrates the pilosebaceous unit over time, affecting resident stem cells and hindering the normal regeneration of the epidermis and adnexal structures, leading to scarring.

This study suggests that PKCß plays a critical role in modulating the dermal inflammatory microenvironment in response to dietary lipids in mice.

According to this worldwide systematic review, psoriasis is a prevalent disease with adult prevalence ranging from 0.53% to 11.48%, more common in older populations and with substantial knowledge gaps in low and middle-income countries.

This review discusses the interplay between hormonal and immune systems in hair follicles and reports no new results, highlighting the need for further research on their role in skin biology and alopecia areata.

In this study, researchers investigated the penetration and cellular responses to nanoplastics in human skin models with compromised barriers, finding that nanoplastics can penetrate the skin, accumulate in cells, and trigger inflammatory responses through specific signaling pathways.

This study found that fermented red ginseng marc alleviated skin lesions, reduced inflammation, and demonstrated antioxidant effects in an AD-like mouse model, suggesting potential therapeutic applications for atopic dermatitis.

In this literature review, it was reported that mental health disorders may both contribute to and be exacerbated by various types of hair loss, and an interdisciplinary treatment model is recommended for effective diagnosis and patient care.

In this animal study, researchers found that local administration of mesenchymal stem cell therapy improved hair regrowth and reduced local inflammatory cytokines in mice with Alopecia Areata, although systemic cytokine levels were unchanged.

This research investigated immune cell involvement in various types of inflammatory alopecia by analyzing gene expression data from scalp samples, revealing distinct cellular changes in conditions like Alopecia Areata, Frontal Fibrosing Alopecia, Lichen Planopilaris, and Central Centrifugal Cicatricial Alopecia, which may inform future therapeutic targets.

In this study, researchers found that the loss of SETDB1 in epidermal keratinocytes led to altered chromatin states, increased ERV expression, and activation of immune responses, while inhibiting these effects with certain antiviral drugs reduced skin inflammation and hair loss in a mouse model.

This study found that Wnt secretion is important for maintaining skin homeostasis in mice, as Evi-deficient mice developed psoriasis-like skin lesions and had an imbalance in immune cell populations.

In this study, researchers developed two novel mouse models to investigate how CD271 deletion in keratinocytes affects skin homeostasis, finding that it leads to changes resembling dysplastic skin conditions with immune cell recruitment and inflammatory cytokine release.

This study found that Botryococcus terribilis ethanol extract significantly reduced inflammation markers in LPS-stimulated RAW264 cells, potentially via Axl inhibition and alteration of immune-related gene expression.

This study highlights that ZNF750, a zinc-finger transcription factor, is crucial for epidermal differentiation and barrier formation in skin by activating genes involved in lipid processing and stratum corneum development, and links ZNF750 sequence variations to skin inflammatory diseases like psoriasis.

In this study, researchers observed distinct aging signatures in mouse keratinocytes, with increased expression in older mice, and noted relevant pathway changes that were also evident in human skin, suggesting potential insights into intrinsic skin aging.

This study detailed distinct immunophenotypic stages of alopecia areata in C3H/HeJ mice, providing an immune blueprint that may help identify therapeutic targets for disease pathways in humans.

This study found that feeding aged mice a probiotic yogurt induced changes leading to thicker, healthier fur, suggesting a bacteria-triggered interleukin-10-dependent mechanism that mimics signs of youth and reproductive fitness.

Permanent hair loss after a stem cell transplant can be a sign of chronic immune system attack on the scalp.

This narrative review reports that IL-17 and IL-23 inhibitors, while effective for psoriasis and other inflammatory diseases, can cause a variety of skin reactions that resemble primary dermatoses, highlighting the need for careful diagnosis and varied management strategies.

This study identified specific genes upregulated in skin γδ T cells involved in alopecia areata, with findings suggesting these cells contribute to disease pathogenesis through inflammatory and Th1 response mechanisms in mouse and possibly human skin.

This study found that camelina oil supplementation was comparable to flaxseed and canola oil in supporting skin and coat health and managing inflammation in dogs over 16 weeks.

This single-patient case study reported promising results for severe, corticosteroid-resistant alopecia areata, with treatment using exosomes derived from mesenchymal stromal cells leading to almost complete hair regrowth in 12 weeks and favorable changes in inflammatory markers, suggesting potential for further investigation.

This study characterized the inflammatory response in a murine burn model, revealing similarities to human burns and supporting the model's use in testing therapies for burn complications.

In this review, researchers concluded that chronic inflammation perpetually activates stem cells, allowing DNA damage accumulation and potentially promoting cancer development and metastasis by converting stem cells into cancer cells.