Dandruff Is a Low-Grade Inflammatory Condition Featuring Hyperproliferative Keratinocytes, Interleukin-17-Producing T Cells, and N-Acyl Ethanolamines

    Alexandra C. Kendall, K.A. Mohamed, Holly Linley … Anna Nicolaou
    Studysummary In this study, researchers observed that dandruff involves altered keratinocyte activity and a low-grade inflammatory response characterized by increased interleukin-17-producing T-cells and CCL17 levels, but without significant changes in immune cell populations or skin barrier lipids.
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    Research cited in this study 4

    1. Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium Cell · 2019
    2. Comparison of Healthy and Dandruff Scalp Microbiome Reveals the Role of Commensals in Scalp Health Frontiers in cellular and infection microbiology · 2018
    3. Stratum Corneum Dysfunction in Dandruff International Journal of Cosmetic Science · 2012
    4. Endocannabinoids Limit Excessive Mast Cell Maturation And Activation In Human Skin Journal of Allergy and Clinical Immunology · 2012