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This study found that a dissolvable microneedle device delivering rapamycin and epigallocatechin gallate nanoparticles significantly enhanced hair regrowth in C57BL/6 mice within 7 days, demonstrating increased hair shaft growth and follicle density with minimal inflammation compared to untreated mice.

This study found that microneedling-induced microinjury in mice promoted hair growth by stimulating the TNF-α/Wnt/VEGF pathway, and blocking TNF-α inhibited this process.

This study explored the development of zinc-incorporated gelatin-based hydrogels, which demonstrated strong antibacterial properties and supported skin cell health, ultimately improving the healing process of S. aureus-infected full-thickness wounds, showing promise as wound dressings for infected wounds.

This study found that EGFR-targeted cancer therapy can cause skin toxicities by disrupting epidermal signaling, allowing microbiota invasion and inflammation, but identified a potential treatment approach using FGF7 or SOS expression to restore barrier integrity.

This study found that during wound healing, hair follicle stem cells develop an immune modulatory ability to create a protective immune suppressive niche, facilitating their survival and function amidst inflammation.

In this study, the high polarity fraction of Lanzhou Fat-Tailed Sheep tail fat showed significant antioxidant and wound healing properties in a mouse model, promoting faster wound closure and reducing inflammation by modulating cytokine levels and enhancing collagen production.

This systematic review explored the potential of cetirizine, an anti-inflammatory antihistamine, as a complementary treatment for androgenetic alopecia, reporting that it might help prevent hair follicle miniaturization by reducing inflammation and modulating immune activity, without notable side effects.

In this study, researchers developed a long-lasting antibacterial coating for medical implants by anchoring silver nanoparticles onto polyamide surfaces, demonstrating potential to improve implant safety and effectiveness by reducing infection and inflammation.

This study concluded that shikonin, a small molecule derived from herbal extract, promotes wound healing and reduces inflammation in mice by activating the PI3K/Akt signaling pathway.

In this study, the authors review how epigenetic regulation influences the role of iPSC-derived neural stem/progenitor cells in spinal cord injury therapy, highlighting challenges in the cells' generation, differentiation, and transplantation, and the effect of therapeutic tools on these processes.

In this systematic review, various nutrients and diets, such as a plant-based diet and supplements like omega-3 fatty acids, were found to impact tissue regeneration, skin health, and wound healing, highlighting the role of nutrient-sensitive signaling pathways in these processes.

This study found that the Nap-F3K-CA hydrogel, when used on burn wounds, demonstrated effective antibacterial and anti-inflammatory properties, promoting accelerated skin repair, decreased wound infections, and improved healing processes, highlighting its potential as a clinical burn wound dressing.

This review discusses a "stochastic multi-hit model" to explain the onset, progression, and recurrence of vitiligo and other autoimmune skin diseases, emphasizing genetic and environmental influences, immune cell interactions, and unexplored mechanistic gaps.

This review examines the regeneration capabilities of skin, oesophagus, and oral mucosa, highlighting the oral mucosa's unique scarless healing properties and the potential of cell therapy to improve scar reduction in wound healing.

This review explores the basic science and therapeutic potential of stem cells, platelet-rich plasma, and exosomes in regenerative medicine, highlighting their promising roles in skin regeneration and repair but noting a need for further research.

This review presents an overview of the integrated organ systems involved in wound healing and reports no new findings; the authors emphasize the roles of blood coagulation, immune response, and cellular mechanisms in tissue repair.

This review examines the role of autophagy, specifically macrophage, chaperone-mediated, and microphagy, in the progression of six skin diseases, including psoriasis and systemic lupus erythematosus, illustrating its significance in cellular homeostasis.

This review summarizes the roles of Wnt signaling in wound healing but presents no new clinical findings, suggesting potential for Wnt-based therapies to enhance tissue regeneration.

This study explored the traditional uses of Trichosanthes cucumerina Linn., or snake gourd, highlighting its application in folk medicine across tropical and subtropical regions to address conditions such as fever, inflammation, digestive disorders, diabetes, and respiratory problems.

In this review, bioengineered materials incorporating growth factors and cytokines were reported to enhance wound healing by sustaining drug delivery, reducing dosage, and minimizing side effects compared to traditional treatments.

This review discusses the developmental regulation of wound healing mechanisms in mammals, focusing on the role of the Wnt and TGF‐β signaling pathways, and reports no new clinical findings.

This review discusses nanoparticle-based wound-healing materials, detailing their benefits, limitations, and recent advancements, and emphasizes the need for further understanding to enhance therapeutic outcomes.

The study suggests that immune privilege collapse in bulge cells and the involvement of pro-inflammatory cytokine interferon-γ contribute to hair follicle stem cell loss in lichen planopilaris.

This article reviews sPLA2-mediated phospholipid metabolism using sPLA2 transgenic/knockout mice and lipid mass spectrometry, offering insights into the distinct roles of sPLA2 enzymes in various biological events.

This review found that microneedling can stimulate various biological pathways to promote tissue remodeling, enhance skin regeneration, and benefit conditions like wound healing and skin rejuvenation, with emerging uses in targeted drug delivery and periodontal therapy.

This review discusses factors influencing angiogenesis, focusing on vascular permeability factor as a key inducer and thrombospondin as a notable inhibitor, and recommends exploring molecular mechanisms for therapeutic interventions.

This review discusses the role of fibroblast heterogeneity in kidney pathology, particularly their contribution to tertiary lymphoid tissue formation, and reports no new results.

This review examines the mechanisms behind pathological scarring like hypertrophic scars and keloids, highlights the limitations of current treatments, and suggests that biomaterial-enabled delivery of anti-fibrotic statins, such as atorvastatin, may offer a promising therapeutic avenue for managing these scars.

This perspective reviews current knowledge about cellular and molecular mechanisms in wound healing from 2023–2025, highlighting inadequately understood pathways associated with conditions like keloids and chronic wounds, and discusses proposed novel therapies for these conditions.

This review highlights zinc's role in health and disease, noting its involvement in immune function and its therapeutic potential for conditions like alopecia areata and psoriasis, but it reports no new clinical results.