Recent Advances in the Controlled Release of Growth Factors and Cytokines for Improving Cutaneous Wound Healing

The document discussed the use of bioengineered materials in improving cutaneous wound healing by providing a biocompatible and degradable environment that mimics the extracellular matrix. These materials facilitated the controlled release of growth factors (GFs) and cytokines, which are crucial for tissue regeneration. The study highlighted that incorporating these factors into biomaterials significantly enhanced wound healing compared to traditional bolus drug treatments. This approach protected the therapeutic agents from degradation, allowed for sustained drug delivery, reduced the required dosage, and minimized the need for repeated administration, thereby decreasing the risk of adverse side effects. The review covered recent advancements in both single and combinatorial delivery methods of GFs and cytokines.