January 2025 in “Sanjeevani Darshan National Journal of Ayurveda & Yoga” This source examines alopecia areata, an autoimmune condition causing patchy hair loss, describing the current reliance on corticosteroid injections despite their severe side effects, and explores Ayurvedic treatments identified as Shaman and Shodhan for managing an equivalent condition called Indralupta.
January 2025 in “Journal of Drugs in Dermatology” This study highlights consensus statements from an expert panel, emphasizing the overlooked role of scalp barrier health in hair growth and dandruff, and notes that most prior research has focused on inflammatory diseases rather than dandruff.
December 2024 in “Indian Dermatology Online Journal” This study established reference values for trichoscopic parameters of hair density and thickness in healthy Indian males, providing a foundation for future research.
November 2024 in “Indus journal of bioscience research.” In this animal study, funnel seed extract significantly reduced insulin and testosterone levels and increased ovulating hormones in rats with induced polycystic ovarian syndrome, suggesting potential hormone-regulating properties.
November 2024 in “Indian Journal of Rheumatology” This study reported that primary care physicians' lack of knowledge about rheumatology and referrals to other specialties are major factors delaying systemic lupus erythematosus patients' access to rheumatology care in India.
November 2024 in “International Journal Of Ayurvedic And Herbal Medicine” In this case report, a 25-year-old male with patchy hair loss showed marked symptomatic improvement following an Ayurvedic treatment regimen at SDM Ayurveda Hospital, supporting Ayurveda's potential effectiveness in managing Indralupta, akin to Alopecia areata.
September 2024 in “Stem Cell Research & Therapy” This study found that extracellular vesicles derived from hyaluronic acid-stimulated induced pluripotent stem cells significantly improved hair growth in a model of androgenetic alopecia in mice by enhancing Wnt/β-catenin signaling and regulating androgen receptor activity, showing comparable results to the commonly used treatment finasteride.
August 2024 in “International Journal of Research in Dermatology” In this randomized, double-blind, placebo-controlled study, Indulekha Svetakutaja Hair Oil significantly reduced dandruff severity compared to coconut oil, with a greater reduction in Total Dandruff scores after 4 weeks of treatment, suggesting it is both safe and effective for dandruff management.
August 2024 in “Indian Dermatology Online Journal” In this retrospective study, researchers described the dermoscopic features of dermatitis cruris pustulosa et atrophicans in 30 patients, finding that follicular-based pustules and other specific features were predominant, with male patients being more affected and primarily involving the lower extremities.
July 2024 in “Indian Journal of Dermatology Venereology and Leprology” This study found that specific PITX2 gene variants are significantly associated with higher risk of androgenetic alopecia in males, highlighting important genetic and environmental interactions influencing its development.
June 2024 in “Regenerative Therapy” This review discussed the potential of induced pluripotent stem cells (iPSCs) for hair follicle regeneration, covering current approaches and challenges, iPSC differentiation, and their possible future clinical applications in hair restoration.
April 2024 in “Histochemistry and cell biology” In this study, NAC was observed to counteract the negative effects of cyclophosphamide on hair follicles in mice, preserving both biochemical parameters and hair structure, suggesting its potential as a therapeutic option for chemotherapy-induced hair loss.
This study found that an extract treatment showed similar efficacy and tolerability to calcipotriol/betamethasone ointment in reducing psoriasis severity and symptoms over 28 days in patients with mild-to-moderate plaque psoriasis.
February 2024 in “International Journal of Research Publication and Reviews” In this case study, researchers observed that Ayurvedic treatments, specifically Praccahnna and Tikta Patola patra swarasa Lepa, improved symptoms of alopecia areata, such as reducing patch size and hair fall.
January 2024 in “International Research Journal of Ayurveda & Yoga” This study reports that in a single-case study, a 24-year-old female with alopecia areata experienced significant hair regrowth after undergoing seven sessions of Jalaukavacharana (leech therapy) along with Ayurvedic medication, suggesting these treatments may be beneficial for such cases.
January 2024 in “The Indian Veterinary Journal” In this case study involving a two-month-old crossbred kid, severe skin conditions characterized by alopecia and pruritic lesions were linked to Malassezia yeast and bacteria, and successful treatment was observed with ketoconazole and supportive care.
January 2024 in “Sanjeevani Darshan National Journal of Ayurveda & Yoga” This study aims to evaluate the efficacy of a treatment approach called Sthanika Chikitsa, involving Shiro Lepa and specific herbal and nasal preparations, for managing Indralupta, a condition akin to Alopecia Areata characterized by hair loss. Results are not provided in the abstract.
January 2024 in “Indian Journal of Pharmaceutical Sciences” In this laboratory study, researchers found that a methanol extract of peach kernel improved the growth and viability of human hair follicle dermal papilla cells, suggesting its potential efficacy for hair growth and care through cell proliferation and signaling pathways activation.
January 2024 in “Journal of Tissue Engineering” In this study, researchers developed self-assembled skin models derived from hair follicle cells, offering an ethical and reliable alternative to animal testing and bovine collagen in dermatological research by providing functional dermal and epidermal layers for substance evaluation.
January 2024 in “Middle East Journal of Applied Science & Technology” This study formulated and evaluated a polyherbal body lotion using neem, tulsi, and aloe vera extracts, finding it met satisfactory physicochemical standards and was well received by users for skin smoothness and hydration without causing allergies.
December 2023 in “Journal of ayurveda and integrated medical sciences” In this case study, a 17-year-old male with patchy hair loss (Indralupta) experienced significant symptom relief after treatment with Pracchanna Karma and Maricha Lepa, suggesting the therapy was effective and economical within a short duration.
December 2023 in “International Journal For Multidisciplinary Research” This source reviews the application of various natural substances, particularly plant extracts from the Ayurvedic system, in promoting hair growth, addressing common issues like pigmentation, dandruff, and hair loss.
December 2023 in “International journal of multidisciplinary research and analysis” In this study, topical administration of secretome hypoxia mesenchymal stem cells gel increased IL-10 and decreased TNF-α gene expression in a fluconazole-induced alopecia-like model in rats, with the 40 μL dose having the most significant effect.
December 2023 in “Medical & Clinical Case Reports Journal” This case study reported significant hair regrowth in a young female patient with alopecia areata after 60 days of Ayurvedic treatment, including leech therapy and herbal medicines, demonstrating its potential effectiveness according to the authors' observations.
December 2023 in “Alzheimer's & dementia” In this rodent study, researchers found that the drug finasteride may reduce anxiety and depression-like behaviors in a model of aging, despite inducing metabolic disturbances and depressive-like behaviors in young rats, suggesting potential considerations for its use in elderly populations.
November 2023 in “Applied sciences” This study found that platelet dry powder can be mass-produced from pig blood by adding calcium chloride, resulting in a stable material with high growth factor concentrations, which could enhance supply for industrial product development.
November 2023 in “ACS Applied Polymer Materials” In this study, the researchers developed a new method using H2O2/TiO2/UV for extracting human hair keratins rapidly, yielding higher protein and enabling the production of keratin films with better hemostatic performance and varied wound-healing properties compared to films from traditionally extracted keratin.
November 2023 in “Indian Journal of Dermatology” This study from North-East India analyzed 21 cases of frontal fibrosing alopecia, noting a high prevalence in post-menopausal women and distinct histological features such as perifollicular lymphocytic infiltrate and hydropic degeneration.
September 2023 in “Indian Journal of Postgraduate Dermatology” In this study, 2% of healthcare workers vaccinated with Covaxin or Covishield reported new skin reactions, with a slightly higher incidence following Covaxin; significant differences were observed among paramedical staff.
September 2023 in “Journal of Education, Health and Sport” This review examines the potential uses of platelet-rich plasma in dermatology, noting its growing therapeutic applications, but highlights the need for more standardized procedures and larger studies to confirm its effects.