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PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

Black ethnicity, prior PSA tests, enlarged prostate, and family history increase prostate cancer risk; Asian ethnicity, obesity, smoking, diabetes, and less sexual activity or no children decrease risk.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.

People with hidradenitis suppurativa often have lower vitamin D levels, weaker hip bones, and altered bone metabolism markers.

Birth control pills with low-dose estrogen and antiandrogenic progestins can effectively treat acne.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

PCOS is a complex condition that affects women's hormonal balance and metabolism, requiring lifestyle changes and medical management.

PCOS increases the risk of heart disease and type 2 diabetes in women.

Older men with lower levels of available testosterone are more likely to be frail.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

Pro-IGF-II improves muscle repair in old mice.

MC-DNA vector-based gene therapy can temporarily treat CBS deficiency in mice.

Overweight women with PCOS have higher levels of certain hormones that could indicate a higher risk of heart and metabolic problems.

Certain MC4R gene variants are linked to higher BMI in obese women with PCOS but do not cause PCOS.

Eating dairy and high glycemic foods may increase the risk of acne.

Obesity may contribute to female hair loss by increasing male hormone levels that affect hair follicles.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

The document concludes that gender-affirming treatments are essential for transgender individuals and outlines safe hormone therapy practices.

PCOS is a common hormonal disorder in women that can lead to various health issues and requires comprehensive management.

Ovulation disorders are a major cause of infertility and menstrual problems in women.

PCOS has a strong genetic basis, but more research is needed to fully understand it.

Combining genetic and physical trait analysis improves diagnosis accuracy for monogenic diabetes.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

PCOS is a genetic disorder affecting women's reproductive health, with treatments focused on symptoms like insulin resistance and fertility.