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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Most skin changes during pregnancy are harmless and temporary, but some can risk the fetus and need careful treatment.

Early diagnosis and treatment of PCOS in teenagers can help prevent more severe adult PCOS.

Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Benign Prostatic Hyperplasia may be caused by changes in how the body processes male hormones.

Hyperpigmentation is common in pregnancy and may not fully fade after birth; melasma, also frequent, can persist but has limited treatment options during pregnancy.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

Certain skin conditions in women are linked to higher risks of metabolic syndrome and type 2 diabetes due to hormone imbalances.

Depression in women with Polycystic Ovarian Syndrome (PCOS) is linked to insulin resistance and hyperandrogenism, and managing these can help reduce depression. Lifestyle changes and Cognitive Behavioral Therapy can be effective treatments.

Estrogen therapy can reduce skin aging but has cancer risks.

Birth control pills with low-dose estrogen and antiandrogenic progestins can effectively treat acne.

Skin problems in the elderly are unique and may indicate other diseases, involving changes in skin, hair, nails, and increased cancer risk.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

SHBG may be a useful early indicator and treatment target for PCOS.

Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Using 5-alpha reductase inhibitors may lower the risk of breast cancer in females.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Estrogen can temporarily slow down hair growth but this can be reversed.

Androgen excess disorders in women were effectively treated with spironolactone, estrogen, and dexamethasone.

Cancer rates are increasing in developed countries, with estrogen, aging, low vitamin D3, and HPV infection as common causes.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

Evening primrose oil significantly improves hormone levels and reduces BMI and cholesterol in women with PCOS.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.