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Biologics for severe asthma have known side effects, but some new risks need more study.

Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.

Hirsutism is mainly caused by high androgen levels or sensitivity, with PCOS being the most common cause.

Isoflavone may help manage PCOS symptoms, but its effectiveness is uncertain.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

FGF21 can help reduce skin inflammation caused by C. acnes.

The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.

Licorice has many health benefits but should be used carefully due to possible side effects.

Probiotics show promise for health benefits but need more research to understand how they work.

Women may need different blood pressure guidelines than men for heart disease prevention.

Keratin proteins are essential for keeping the cells in the human colon healthy and stable.

Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.

Hair glucocorticoid levels and gut bacteria are linked to growth rates in piglets.

Taurine is important for many body functions and its deficiency can cause health problems.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Retinoic acid affects male and female muscle energy use and function differently.

Testosterone's role in women's sex drive is unclear and needs more research, as low levels don't always mean less sexual interest and high levels can cause side effects.

Taking high doses of fluconazole for a long time can cause reversible hair loss.

SCD1 is crucial for skin health and overall energy balance.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Skin cells from people with Epidermolysis Bullosa Simplex have abnormally placed and less active mitochondria.

Syndecan-1 is essential for maintaining skin fat and preventing cold stress.

Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.

Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.

Autophagy helps activate hair stem cells and hair growth by changing their energy use to glycolysis.

Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.