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Tofacitinib regrew hair in a man with total hair loss but raised cytokine levels, needing more research on possible side effects.

Alopecia Areata is linked to specific gut bacteria and metabolites, indicating a complex gut microbiome.

Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.

Enzymes called PADIs play a key role in hair growth and loss.

Hormones like androgens, estrogen, thyroid hormones, and stress hormones can contribute to hair loss, and treatments target these hormonal imbalances.

Cancer treatment drugs can cause permanent hair loss by damaging hair follicle stem cells, but a specific inhibitor might reverse this effect.

A woman's hair loss worsened after starting hepatitis C treatment due to immune changes in her hair follicles.

IL-15 promotes hair growth and protects hair follicles.

Restoring immune privilege in hair follicles could help treat certain types of hair loss.

Ruxolitinib may help treat hair loss by reducing inflammation, promoting hair growth signals, and protecting hair follicle immunity.

Alopecia areata is caused by immune system issues, and JAK inhibitors might help treat it.

Understanding the immune-related causes of Alopecia Areata has led to potential treatments like JAK inhibitors.

Blocking TYK2 might be a new way to treat hair loss from alopecia areata.

Alopecia areata, a common autoimmune hair loss condition, often runs in families.

New treatments for alopecia areata, like JAK inhibitors and immunomodulators, are promising.

Neurotrophins are important for hair growth and response to stress.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Alopecia areata is a common autoimmune disease affecting hair follicles, with unclear causes and a need for better treatments.

Hair follicles prevent NK cell attacks to avoid hair loss.

The nail matrix has a reduced immune response, protecting it from autoimmunity.

Dandruff is linked to increased T cells and weakened immune protection in hair follicles.

Interleukin-15 can help hair growth and protect hair follicles.

Hair follicles could help develop eye treatments by studying immune responses.

Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.

Decreased CD200 in hair follicles may cause immune issues in some alopecia areata cases.

Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.

Alopecia areata involves complex immune and genetic factors, with potential treatment targets identified, but more research is needed.

Tofacitinib was more effective than apremilast in treating hair loss in a mouse model of alopecia areata.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

Mesenchymal stem cell therapy may help treat alopecia areata by promoting hair growth and reducing inflammation.