181 citations,
December 2017 in “Trends in immunology” Intestinal intraepithelial lymphocytes are crucial for gut immunity and maintaining the mucosal barrier.
23 citations,
January 2016 in “Frontiers in immunology” Using low-dose IL-2 to increase regulatory T cells might be a safe way to treat type 1 diabetes without severe side effects.
15 citations,
January 2023 in “Antioxidants” Oxidative stress plays a significant role in alopecia areata, and new treatments may include JAK inhibitors and antioxidants.
13 citations,
November 2017 in “Journal of Cellular and Molecular Medicine” The workshop discussed the role of a protein called calreticulin in health and disease, its potential as a treatment target, and its possible use as a disease marker.
1 citations,
April 2023 in “International Journal of Molecular Sciences” Botryococcus terribilis Ethanol Extract may reduce inflammation by changing gene expression in cells.
November 2023 in “BMC genomics” The study concluded that the arachidonic acid pathway and the protein KRT79 play a role in determining the fineness of cashmere.
November 2023 in “Journal of Drug Delivery Science and Technology” Exosomes may help stimulate hair growth and improve hair loss conditions like androgenic alopecia.
127 citations,
April 1999 in “Journal of Investigative Dermatology” Rodent models helped understand psoriasis but none perfectly replicated the disease.
22 citations,
September 2019 in “Trends in Immunology” Acne is a temporary skin imbalance during puberty that often resolves on its own.
April 2019 in “Journal of Investigative Dermatology” Eating grape powder may reduce the severity of skin allergy symptoms.
56 citations,
October 2016 in “Journal of dermatological science” New insights into the causes and treatments for the autoimmune hair loss condition Alopecia areata have been made.
113 citations,
June 2019 in “F1000Research” Scarless healing is complex and influenced by genetics and environment, while better understanding could improve scar treatment.
24 citations,
January 2008 in “KARGER eBooks” The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.
23 citations,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Alopecia Areata is an autoimmune disease affecting hair follicles, influenced by genetic and environmental factors, with rodent models being essential for research.
16 citations,
December 2021 in “Frontiers in Endocrinology” Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.
9 citations,
September 2009 in “PubMed” Antigen presenting cells around hair follicles are crucial in SLE-related hair loss.
2 citations,
October 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” AIRE deficiency causes hair loss similar to alopecia areata in mice.
1 citations,
July 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” Light affects skin health, aging, and cancer risk, and new light-based treatments and imaging are promising for skin care.
April 2023 in “IP Indian journal of clinical and experimental dermatology” Lichen planus is a chronic autoimmune disease that is hard to treat and more common in women.
4 citations,
March 2022 in “BioEssays” Hydra can help understand human hair follicle microbiomes and develop new skin disease therapies.
22 citations,
January 2009 in “Advances in experimental medicine and biology” FOXN1 mutations cause severe immunodeficiency, hair loss, nail issues, and thymus defects.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” The study suggests a link between varicella-zoster virus and segmental vitiligo, with evidence of the virus disrupting skin pigment cells.
717 citations,
June 2010 in “Nature” Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.
6 citations,
May 2013 in “The Journal of Dermatology” Autoimmune reactions may cause both alopecia areata and HAM.
August 2023 in “Medical Hypotheses” Metformin, usually used for diabetes, can also help treat hair loss from alopecia areata due to its ability to reduce inflammation and stimulate new hair growth.
69 citations,
February 2008 in “The American journal of pathology” Controlled delivery of specific RNA and IL-4 restored hair growth in mice with autoimmune alopecia.
7 citations,
July 2013 in “InTech eBooks” Oral lichen planus is a chronic disease causing mouth discomfort and sometimes needs immunosuppressive treatment.
5 citations,
October 2012 in “Veterinary Pathology” A Doberman Pinscher had a rare form of autoimmune disease causing hair loss and other severe symptoms.
194 citations,
October 2018 in “Microbiome” Acne is linked to complex skin microbe interactions, and new findings suggest microbiome-based treatments could be effective.
29 citations,
April 2000 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry” ICAM-1 helps regulate hair growth cycles and skin remodeling.