57 citations
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April 2019 in “British journal of dermatology/British journal of dermatology, Supplement” This background review discusses alopecia areata, highlighting the role of CD8+NKG2D+ T cells in hair follicle pathogenesis, and notes that the exact mechanisms causing hair loss remain unclear.
52 citations
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October 2012 in “Journal of Dermatological Science” This review presents updated tables of mouse mutants with hair growth abnormalities to aid in understanding the molecular mechanisms of human hair disorders, but reports no new clinical results.
48 citations
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January 2000 in “Hormone Research in Paediatrics” This article reviews the regulation of androgens in human skin and adrenals, highlighting their role in skin disorders, but reports no new research findings.
46 citations
,
January 1996 in “Journal of The American Academy of Dermatology” This study identified the presence of apoptotic or necrotic keratinocytes and hair shaft dystrophy as potential markers of hair loss in patients with HIV-1 infection.
41 citations
,
September 2012 in “Cellular and Molecular Life Sciences” This review summarizes the current understanding of microRNAs in skin biology, highlighting their roles in processes like wound-healing and aging, without presenting any new experimental results.
25 citations
,
December 1992 in “Seminars in cell biology” This review discusses how epidermal Langerhan's cells and dermal cells may influence keratinocyte environments, potentially aiding in the formation of stem cell niches and cellular variety in the basal layer, without providing novel results.
19 citations
,
November 2023 in “npj Regenerative Medicine” This study found that synthetic melanin particles applied topically in mouse injury models improved wound healing, showing potential as a therapy for accelerated healing, including in human skin explants.
18 citations
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November 2020 in “Frontiers in Cell and Developmental Biology” This review discusses how inflammation influences hair follicle stem cell activities like wound healing and follicle cycling and suggests a potential link between inflammation, stem cell activation, and programmed cell death.
13 citations
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July 2004 in “Skinmed” This article reviews the structure and function of hair follicles, diagnostic approaches, and treatments for nonscarring alopecias, but reports no new clinical results.
7 citations
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June 2019 in “Cureus” This literature review suggests that fractional lasers and microneedling, particularly when used with topical agents, may be effective treatments for alopecia areata; however, the small size and number of studies highlight a need for larger trials to confirm efficacy.
7 citations
,
February 2018 in “InTech eBooks” This article reviews how biomaterials and stem cells could advance regenerative medicine but does not report new results, emphasizing the potential of combining novel biomaterials with stem cells for effective therapies.
7 citations
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January 2013 in “Journal of Investigative Dermatology” This study suggests that dietary vitamin A may influence alopecia development and progression, but the mechanisms remain unclear, highlighting the interplay between genetics and nutrition in these hair loss conditions.
4 citations
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November 2023 in “Frontiers in immunology” In this narrative review, researchers outlined the role of T cells in the autoimmune pathogenesis of alopecia areata and highlighted ongoing research into therapeutic pathways, beyond current JAK inhibitors, aimed at developing new treatments for the disease.
3 citations
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December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study revealed key cellular dynamics and interactions during early embryonic mouse skin development, highlighting complex transitions from precursor states to diverse multilayered structures.
3 citations
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May 2018 in “InTech eBooks” This review discusses the evaluation of animal models for hair research and regeneration, highlighting their importance and limitations, and calls for improved approaches to advance understanding of human hair diseases.
2 citations
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October 2015 in “Human Gene Therapy” The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.
1 citations
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January 2026 in “Frontiers in Cell and Developmental Biology” This study reviews the transformative role of artificial intelligence in biomaterial design, highlighting its ability to reduce costs through virtual screening, enhance material performance, and predict biological interactions to advance personalized and precision medicine.
1 citations
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September 2025 in “Frontiers in Immunology” In this study, researchers using a Treg-specific HuR-deficient mouse model found that the RNA-binding protein HuR is crucial for stabilizing Foxp3 mRNA, affecting Treg function and immune regulation, with HuR disruption leading to impaired Foxp3 expression and potential autoimmune dysfunction.
June 2026 in “Research Square” This report on a case of alopecia areata in a mother and daughter with a 16-year gap suggests genetic predisposition and environmental triggers rather than direct transmission.
February 2026 in “International Journal of Web of Multidisciplinary Studies” This review synthesizes current research on how the interaction between the skin microbiome and exosome-mediated communication influences hair disorders, and discusses how microbiome restoration and exosome-based therapies could advance treatments for conditions like alopecia by promoting hair regrowth and follicular health.
October 2025 in “Scientia Generalis” In this narrative review, dysbiosis was found to potentially influence androgen metabolism and immune response, suggesting that gut microbiota balance may play a role in the prevention and treatment of androgenetic and areata alopecia.
October 2025 in “Clinical Cosmetic and Investigational Dermatology” This study synthesizes knowledge of how dendritic cell signals, epithelial integrins, and fibroblast activity converge on TGF-β1 to maintain or disrupt skin healing, contrasting normal and fibrotic scar formation and suggesting possible integrin and immune-targeted treatments for skin fibrosis.
This chapter reviews the challenges and future prospects of using nanotechnology and phytochemistry in developing safe, effective, and precision-based therapies for Polycystic Ovary Syndrome, without reporting new clinical findings.
January 2025 in “UiTM Institutional Repositories (Universiti Teknologi MARA)” This abstract introduces dandruff as a key obstacle to achieving beautiful hair and a healthy scalp, noting its impact on appearance and self-confidence, but it does not provide study results.
January 2025 in “RSC Pharmaceutics” Smart microneedles using advanced tech could improve psoriasis treatment.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that AP-2α and AP-2β transcription factors are crucial for maintaining adult skin homeostasis, with their inactivation in keratinocytes leading to impaired differentiation, hair abnormalities, and inflammation, highlighting their key regulatory roles.
May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that hair-type tissues in hedgehogs show higher enrichment of immune-related genes compared to spine-type tissues, suggesting that spines evolved to protect against injuries and infections.
December 2016 in “Journal of evolution of medical and dental sciences” This study reported common skin changes and symptoms associated with thyroid disorders, such as dry skin in hypothyroidism and warm, soft skin in hyperthyroidism, and noted urticaria as a frequent autoimmune association in hypothyroid patients.
September 2014 in “Aktuelle Dermatologie” This symposium review highlights past, present, and future developments in skin research, celebrating the work of Prof. Johanna Brandner and Dr. Peter Arne Gerber, without reporting new clinical results.
129 citations
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November 2005 in “Internal Medicine Journal” This article reviews the recognition and management of Staphylococcus aureus toxin-mediated diseases, but it does not present new research findings.