research Epidermal Abnormalities and Increased Malignancy of Skin Tumors in Human Epidermal Keratin 8-Expressing Transgenic Mice
Mice with human skin protein K8 had more skin problems and cancer.
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research Epidemiology of Vitiligo, Associated Autoimmune Diseases, and Audiological Abnormalities: Ankara Study of 80 Patients in Turkey
Vitiligo is linked to autoimmune diseases and hearing issues, so hearing tests are recommended for patients.
research Efficacy and Safety of Persimmon Leaf Formulated With Green Tea and Sophora Fruit Extracts on Hair Growth: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
BLH308, with persimmon leaf, green tea, and sophora fruit extracts, safely increased hair density and thickness.
research Age- and Sex-Dependence of Five Major Elements in the Development of Human Scalp Hair
Calcium and magnesium in hair increase with age and are higher in adult women.
research Different Levels of EGF, VEGF, IL-6, MCP-1, MCP-3, IP-10, Eotaxin, and MIP-1α in the Adipose-Derived Stem Cell Secretome in Androgenetic Alopecia
Certain proteins are found at higher levels in balding areas compared to non-balding areas, suggesting a link to hair loss. This could be useful for diagnosing and treating hair loss.
research Versatile Use of Submental Tissue for Reconstruction of Perioral Soft Tissue Defects
Submental tissue is good for repairing mouth area skin with minimal scarring and good cosmetic results.
research Pregnancy in Postpartum Estrus Induces Inflammatory Milk Production and Catagen-Specific Pup Skin Inflammation in Interleukin-10 Deficient Mice
Pregnancy right after giving birth in mice lacking IL-10 causes milk that leads to liver issues and hair loss in their babies.
research Inappropriate Sexual Behaviors in Patients with Vascular Dementia: Possible Response to Finasteride
Finasteride may help reduce inappropriate sexual behaviors in dementia patients with prostate issues.
research Effect of Needle Geometry on Insertion Force of Different Hair Implanters
Needle shape affects the force needed for hair implants, with certain shapes reducing the effort required.
research Hair Follicle-Derived IL-7 and IL-15 Mediate Skin-Resident Memory T Cell Homeostasis and Lymphoma
Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.
research Association of Benign Prostatic Hyperplasia with Male Pattern Baldness
Men with enlarged prostates often have more severe baldness.
research Hair Repigmentation Associated with the Use of Lenalidomide: Graying May Not Be an Irreversible Process
An 81-year-old man's white hair began to regain its original color while he was treated with lenalidomide, suggesting that graying hair might be reversible.
research Transgenic Kallikrein 14 Mice Display Major Hair Shaft Defects Associated with Desmoglein 3 and 4 Degradation, Abnormal Epidermal Differentiation, and IL-36 Signature
Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.
research Erlotinib-Induced Skin Inflammation Is IL-1 Mediated in KC-Tie2 Mice and Human Skin Organ Culture
Erlotinib causes skin inflammation through IL-1, which can be reduced by anakinra.
research Evaluation of Serum Levels of IL-6, IL-10, and TNF-a in Alopecia Areata Patients: A Systematic Review and Meta-Analysis
Alopecia areata patients have higher levels of IL-6 and TNF-α.
research Ovarian Leydig Cell Hyperplasia as a Rare Cause of Hair Loss in a Postmenopausal Female Patient: A Case Report and Diagnostic Approach Toward Postmenopausal Hyperandrogenism
An 84-year-old woman's hair loss was due to a rare condition called Leydig cell hyperplasia, which was treated with surgery.
research CGF Therapy: Bridging Androgenetic Alopecia Observations to Psoriasis Treatment via IL-17 Pathway
CGF therapy may effectively treat psoriasis by reducing inflammation.
research 1,25-(OH)2D3 Promotes Hair Growth by Inhibiting NLRP3/IL-1β and HIF-1α/IL-1β Signaling Pathways
1,25-(OH)2D3 helps hair grow by blocking certain harmful signals.
research IL-17 Expression in Perifollicular Fibrosis in Biopsies from Lichen Planopilaris
Blocking IL-17 might help treat the hair loss condition Lichen planopilaris.
research Analysis of the Mechanism of IL-36α in Wound-Induced Hair Follicle Neogenesis
IL-36α helps in growing new hair follicles when healing wounds, potentially aiding in hair growth.
research Dermatologic Changes Associated With Interleukin 2 Administration
IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.
research Low-Dose IL-2 for Treating Moderate to Severe Alopecia Areata: A 52-Week Multicenter Prospective Placebo-Controlled Study Assessing Its Impact on T Regulatory Cell and NK Cell Populations
The study's results on the effectiveness of low-dose IL-2 for alopecia areata and its impact on immune cells were not provided.
research Treatment of Keratosis Pilaris With 810-nm Diode Laser
The 810-nm diode laser improves skin texture in keratosis pilaris but not redness.
research Interleukin-6 Null Mice Paradoxically Display Increased STAT3 Activity and Wound-Induced Hair Neogenesis
Mice without the IL-6 gene had more hair growth after injury due to higher activity of a related protein, Stat3.
research A Potential Role for IL-4 and IL-13 in an Alopecia Areata–Like Phenotype: A Clinical Perspective
IL-4 and IL-13 might play a role in a type of hair loss similar to alopecia areata.
research Correlation Between Individual Inflammation Genetic Profile and Platelet-Rich Plasma Efficacy in Hair Follicle Regeneration: A Pilot Study Reveals Prognostic Value of IL-1α Polymorphism
Your genes, especially IL-1a, can predict how well a hair growth treatment with platelet rich plasma will work for you.
research Chinese SLE Treatment and Research Group Registry XIII: Prevalence and Risk Factors for Chronic Scarring Alopecia in Patients with Systemic Lupus Erythematosus
About 8% of people with systemic lupus erythematosus have chronic scarring alopecia, with certain symptoms and positive antibodies increasing the risk, while immunosuppressants may lower it.
research Adipose Tissue Remodeling via TSLP-Mediated IL-4/IL-13 Signaling: Implications for Atopic Dermatitis and Skin Barrier
TSLP affects atopic dermatitis by increasing sebum and reducing fat through IL-4/IL-13 signaling.
research Editors' Picks
Small molecule DMF improves psoriasis and multiple sclerosis, adult skin cells can be made to grow new hair, certain skin cells initiate hair growth, IL-17C controls gut health and can cause skin inflammation, and skin cells produce IL-17 that can lead to psoriasis.
research Editors' Picks
New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.