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Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

An imbalanced gut and lack of biotin can cause hair loss in mice.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

Stress can worsen skin conditions by affecting hormone levels and immune response.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Platelet-rich plasma, taken from a person's own blood, can help rejuvenate skin, stimulate hair growth, and treat hair loss, but more research is needed to confirm its safety and effectiveness.

New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.

Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.

Skin fat plays a key role in immune defense and healing beyond just storing energy.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.

MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Thymic transplantation normalized some T-cells but not others, maintaining immune function.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

Bariatric surgery affects skin health, causing both direct complications and changes in existing skin conditions, often related to nutritional deficiencies.