research Omenn Syndrome in a 10-Month-Old Male With Athymia and VACTERL Association
A 10-month-old boy with a rare combination of genetic conditions has severe immune deficiency and treatment challenges.
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120-150 / 1000+ results research Preclinical Pharmacology, Antitumor Activity, and Development of Pharmacodynamic Markers for the Novel, Potent AKT Inhibitor CCT128930
CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.
research Mutations in SREBF1, Encoding Sterol Regulatory Element Binding Transcription Factor 1, Cause Autosomal-Dominant IFAP Syndrome
Changes in the SREBF1 gene cause a rare genetic skin and hair disorder.
research Sex Differences in Animal Models of Sodium Valproate-Induced Autism in Postnatal BALB/c Mice: Whole-Brain Histoarchitecture and 5-HT2A Receptor Biomarker Evidence
Male mice are more susceptible to autism-like changes from valproic acid than female mice.
research Cellular Therapeutics and Immunotherapies in Wound Healing – On the Pulse of Time?
Cellular and immunotherapies show promise for healing chronic wounds but need more research.
research Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity
A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.
research Coexistence of Dermatomyositis and Alopecia Areata: Insight into Pathogenesis
DM and AA may share a common cause.
research Pemphigus and Associated Comorbidities: A Cross-Sectional Study
People with pemphigus are more likely to have conditions like hypothyroidism, inflammatory bowel disease, and diabetes.
research Fine Mapping of the Human AR/EDA2R Locus in Androgenetic Alopecia
Genetic marker rs12558842 strongly linked to male hair loss.
research Direct Implantation of Hair-Follicle-Associated Pluripotent Stem Cells Repairs Intracerebral Hemorrhage and Reduces Neuroinflammation in Mouse Model
Implanting hair-follicle stem cells in mice brains helped repair brain bleeding and reduced brain inflammation.
research Syphilitic Alopecia: Case Reports and Trichoscopic Findings
Hair loss due to syphilis can be identified using trichoscopy and is treatable with antibiotics.
research Combining 308-Monochromatic Excimer Phototherapy with Monthly IM Triamcinolone Acetonide for the Treatment of Resistant Alopecia Totalis
The combination therapy was effective and well-tolerated, especially in young patients.
research Obesity and the Skin
Obesity is linked to various skin problems and may increase the risk of skin cancer.
research Review Article: Dermatological Complications of Immunosuppressive and Anti-TNF Therapy in Inflammatory Bowel Disease
Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.
research Prolactin Delays Hair Regrowth in Mice
Prolactin slows down hair growth in mice.
research Significance of the S100A4 Protein in Psoriasis
The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.
research Hydrogen Peroxide Disrupts Scarless Fetal Wound Repair
Hydrogen peroxide can cause scars by changing healing processes and increasing certain protein levels.
research Lupus Panniculitis Clinically Simulating Alopecia Areata
Lupus can look like hair loss from alopecia areata but needs different treatment.
research PKC Downregulation Upon Rapamycin Treatment Attenuates Mitochondrial Disease
Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.
research Ganoderma Lucidum as an Inhibitor of Testosterone-Induced Prostatic Hyperplasia in Rats
Ganoderma lucidum may help treat enlarged prostate in rats.
research Hair and Scalp Disorders in Women of African Descent: An Overview
The document concludes that clinicians should be aware of common hair and scalp disorders in women of African descent and that more research is needed to develop effective treatments.
research Peripheral Blood Gene Expression in Alopecia Areata Reveals Molecular Pathways Distinguishing Heritability, Disease, and Severity
Blood tests can help understand the genetic differences in people with alopecia areata, including how severe it is and if it's inherited.
research Localized Cutaneous Necrosis Associated with the Antiphospholipid Syndrome
A woman with lupus experienced skin death due to a blood clotting disorder after stopping a blood thinner, which healed with treatment.
research Contact Dermatitis to Phenol-Formaldehyde Resin in Two Plywood Factory Workers
Two plywood factory workers developed contact dermatitis from phenol-formaldehyde resin, a known allergen.
research Human Epithelial Stem Cell Survival Within Their Niche Requires Tonic Cannabinoid Receptor 1 Signaling—Lessons From the Hair Follicle
Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.
research Urticaria Neonatorum: Accumulation of Tryptase-Expressing Mast Cells in the Skin Lesions of Newborns with Erythema Toxicum
Newborns with the common rash Erythema Toxicum have many active mast cells in their skin, but these cells don't produce the LL-37 peptide.
research Letters to the Editor: Case Reports and Studies in Dermatology
Careful management of blood thinners is crucial for lupus patients with APS.
research Androgenetic Alopecia May Be Associated With Weaker COVID-19 T-Cell Immune Response: An Insight Into a Potential COVID-19 Vaccine Booster
Hair loss may link to weaker COVID-19 immunity, suggesting possible need for extra vaccine boost.
research Dermatophytosis Caused by a Chrysosporium Species in Two Cats in Turkey: A Case Report
Two cats and their owner in Turkey were successfully treated for a rare fungal infection with fluconazole.
research Mesenchymal Stem Cell-Derived Protein Extract Induces Periodontal Regeneration
MSC-protein helps regenerate gum tissue and bone.