Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that older men with vertex balding had lower levels of IGFBP-3 and higher levels of IGF-1 in their plasma.

This study found that older men with vertex balding have lower circulating levels of the protein IGFBP-3 and higher levels of IGF-1.

In this case-control study, researchers observed that women with female pattern hair loss exhibited significantly lower serum IGF-1 levels than controls, while IGFBP-3 levels showed no significant difference, suggesting a potential role for IGF-1 in the condition.

This study found that women with female pattern hair loss had significantly lower serum IGF-1 levels than controls, suggesting a possible role for IGF-1 in this condition.

This study found that women with female pattern hair loss had significantly lower serum IGF-1 levels compared to controls, but no significant association between IGFBP-3 levels and hair loss severity was observed.

This study found that cortisol increases mac25/IGFBP-rP1 expression in osteoblast-enriched cells from fetal rat calvariae, indicating transcriptional regulation which may influence IGF and insulin effects in bone.

This review discusses the effects of IGF-1 on hair follicle cell proliferation and differentiation, highlighting its roles in paracrine signaling, apoptosis prevention, and hair growth, but reports no new clinical results.

This study found that IGF1, retinoic acid, and dexamethasone increase IGFBP-3 production in cultured human dermal papilla cells, potentially inhibiting IGF1 action on hair growth.

This study suggests that 5α-reductase-mediated metabolism of progesterone contributes to the differentiation of endometrial stromal cells, potentially influencing progesterone levels and promoting cell differentiation.

This investigation found that certain supplements, particularly whey protein isolate, growth hormones, and anabolic steroids, can negatively impact hair loss by affecting biochemical pathways.

This study found that citron seed oil promotes hair regrowth in a C57BL/6 mouse model by enhancing the transition to the growth phase, increasing hair follicle features and skin thickness, and inducing specific protein expressions that support hair regeneration.

This study found that in mice, inactivating beta-catenin in the dermal papilla reduces hair follicle progenitor proliferation and disrupts the hair cycle.

This study found that dermal papilla cells from balding scalp follicles secrete significantly less insulin-like growth factor-1 and its binding proteins, suggesting a mechanism contributing to male pattern baldness.

This study found that photobiomodulation-irradiated conditioned medium from human adipose-derived stromal cells enhanced hair growth in mice, suggesting its potential as a treatment for hair loss by increasing growth factor secretion.

This study suggests that IGFBP-2 may play a role in basal cell carcinoma development by mediating epidermal progenitor cell expansion in hair follicles with activated Shh signaling.

This perspective discusses Villani et al.'s findings on the role of the IGF regulatory protein Igfbp2 in basal cell carcinogenesis and highlights potential therapeutic and preventive targets, while raising questions about the cell of origin.

This review highlights LTBP1 as a critical integrator in disease processes, showing its dual role in cancer progression and suppression, its pathological influence in fibrosis, and its contribution to various disorders, suggesting its potential as a biomarker and therapeutic target.

This study observed that the OCIAD2 and DCN genes in Liaoning cashmere goats have opposite effects on hair growth by interacting with the TGF-β signaling pathway, influencing follicle morphogenesis and periodic changes.

This review discusses the use of platelet-rich plasma for treating various types of alopecia, reporting promising preliminary hair regrowth results but noting a lack of quantitative evidence from well-designed clinical trials.

This study found that patients with acne vulgaris had higher serum IGF-1 levels and more intense FoxO1 and mTOR expression than controls, suggesting their role in acne pathogenesis.

In this study, pantothenic acid at 20 μg/ml was observed to promote dermal papilla cell proliferation and migration, likely through up-regulation of ID3 and inhibition of Notch signaling.

This study found significant changes in gene and protein expression related to hair follicle development in Rex rabbits' skin during the first 8 weeks of life.

This study suggests that edelweiss extract may promote hair growth and reduce shedding in ex vivo experiments by affecting hair follicle anagen phase duration and keratinocyte proliferation.

This review discusses how Western diet may contribute to acne vulgaris through insulin signaling and metabolomic changes, promoting a dietary approach for management, but reports no new experimental results.

In this study, topical piperonylic acid was found to improve wound healing in mice by activating EGFR and modulating gene expression related to the healing process.

This research found that kaempferol, a flavonoid from hair growth-promoting plants, significantly enhanced human dermal papilla cell proliferation and inhibited specific signaling pathways, outperforming minoxidil, with topical application in mice promoting hair growth and thickness, indicating potential as a natural hair loss treatment.

This study suggests that an extract from Malva verticillata seeds could help treat hair loss by modulating the Wnt/β-catenin pathway in cultured human dermal papilla cells.

This study found that sex hormone-binding globulin promotes facial aging, while sex steroid hormones such as testosterone and estradiol inhibit it, with growth hormone levels showing no significant effect.

This study found that zebrafish and stickleback fish use similar genetic programs for tooth regeneration, despite differences in their dental structures.

This study synthesizes knowledge of how dendritic cell signals, epithelial integrins, and fibroblast activity converge on TGF-β1 to maintain or disrupt skin healing, contrasting normal and fibrotic scar formation and suggesting possible integrin and immune-targeted treatments for skin fibrosis.