research Identification of a Novel Three-immunogene Diagnostic Signature for Alopecia Areata
This study established an IRGDS model with diagnostic capability for alopecia areata, which may serve as an auxiliary marker for the condition.
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research Identification and expression of the target gene SLC24A2 of oar-miR-377 and its novel SNPs effects on wool traits in sheep
This study found that in sheep, the microRNA oar-miR-377 regulates hair follicle development by targeting the SLC24A2 gene, and identified a genetic variation associated with wool quality, suggesting potential markers for breeding.
research Identification of Potential Cytochrome p450c 17 Alpha Inhibitors for the Treatment of PCOS via Scaffold Hopping and Fragment-Based De-Novo Drug Design
This study identified seven novel CYP17A1 inhibitor scaffolds as potential leads for treating polycystic ovary syndrome through an in silico approach, demonstrating favorable interactions, drug-like properties, and predicted bioactivities warranting further experimental validation.
research Identification of Familial Infections Using Multilocus Microsatellite Typing in Tinea Corporis due to Microsporum canis
This study reported three cases of tinea corporis caused by Microsporum canis in a household, linked to a domestic cat, where genetic analysis suggested a familial transmission route.
research Identification and Expression of the Target Gene SLC24A2 of oar-miR-377 and Its Novel SNPs Effects on Wool Traits in Sheep
In this study, researchers found that oar-miR-377 regulates secondary hair follicle development in sheep by downregulating the SLC24A2 gene, and a specific SNP in oar-miR-377 is significantly associated with wool fiber diameter variation in Chinese Merino sheep.
research Identification of Potential miRNA–mRNA Regulatory Network Associated with Growth and Development of Hair Follicles in Forest Musk Deer
In this study, researchers analyzed miRNA and gene expression in the hair follicles of FMD during different hair cycle stages, identifying differential expression patterns and key pathways involved in hair follicle development and growth.
research Identification of N6-Methyladenosine-Related Factors and the Prediction of the Regulatory Mechanism of Hair Follicle Development in Rex and Hycole Rabbits
This study investigated m6A RNA modification in hair follicle development, finding that Hycole rabbits displayed longer hair, higher primary hair follicle ratios, and thicker skin compared to Rex rabbits, while also identifying key differential genes and pathways involved in hair growth.
research Identification of immune microenvironment changes, immune-related pathways and genes in male androgenetic alopecia
This study found increased infiltration of specific immune cells, such as γδ T cells and CD8+ T cells, in the bald scalp of male androgenetic alopecia patients, and identified four key immune-related genes potentially involved in hair loss development through interferon-γ signaling pathways.
research Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular cells
In this study, FOL-026, a peptide based on osteopontin, was shown to promote angiogenesis and stimulate vascular cell proliferation and migration through neuropilin-1, similar to VEGF, suggesting potential therapeutic applications in vascular repair and angiogenesis-related conditions.
research Identifying critical cell types and gene regulatory pathways for hair and skin disease
Researchers identified key cell types and genes involved in hair and skin diseases.
research Identification of Distinct Immune Signatures and Chemokine Networks in Scalp Inflammatory Diseases
This study identified shared gene expression changes and immune cell infiltration patterns that may contribute to hair loss in alopecia areata and cutaneous lupus erythematosus, but also highlighted factors that might preserve hair in psoriasis patients.
research Identification of BST2 as a biomarker for alopecia areata in both mice and humans
In this study, researchers found that BST2 expression is significantly upregulated in skin sections of mice with alopecia areata, implicating BST2's role in the disease pathogenesis through the action of epidermal γδ T cells and macrophages.
research Identification of ectoparasitic insects among domestic goats in Bulgaria
This study identified six species of ectoparasitic insects infesting domestic goats in Bulgaria, with Linognathus stenopsis being the most prevalent across the surveyed farms.
research Identification of Biomarkers in Affected Hair Follicles from Chronic Discoid LupusErythematosus by Weighted Gene Co-Expression Network Analysis
In this study, type I interferon response-related genes activated by RIG-1 and IL-17 signaling pathways were significantly up-regulated in both hair follicles and skin tissues affected by chronic discoidal lupus erythematosus.
research Identification of Biomarkers in Affected Hair Follicles from Chronic Discoid Lupus Erythematosus by Weighted Gene Co-Expression Network Analysis
This study found that type I interferon response-related genes activated by RIG-1 and IL-17 pathways were significantly up-regulated in hair follicle and skin samples with chronic discoidal lupus erythematosus.
research Identification of a novel homozygous LAMB3 mutation in a Chinese male with junctional epidermolysis bullosa and severe urethra stenosis: A case report
This case study reports a new LAMB3 mutation linked to junctional epidermolysis bullosa with severe urinary tract stenosis, outlining treatment challenges and expanding knowledge of EB-related urological complications.
research Identification of the KAP27-1 gene in sheep and its effect on wool traits
This study found that variation in the ovine KRTAP27-1 gene may influence wool growth, with certain genotypes associated with higher mean staple length and greasy fleece weight in sheep.
research Idiopathic unilateral facial hirsutism
This case report details a 40-year-old woman with idiopathic hirsutism, as she exhibited terminal hair on the left side of her chin without signs of hyperandrogenism.
research Identifying Long-Term Effects of SARS-CoV-2 and Their Association with Social Determinants of Health in a Cohort of Over One Million COVID-19 Survivors
This study found that numerous long-term effects of SARS-CoV-2 were significantly associated with age and gender, while race, income, and education had limited significance.
research Identification of seven new prostate cancer susceptibility loci through a genome-wide association study
In this study, researchers identified seven new genetic loci associated with prostate cancer susceptibility through a multi-stage genome-wide association study.
research Identification compounds fruit of Ziziphus jujube Mill hydroethanoly extract and evaluation of Its antifungal effect on blanched corn grains
Ziziphus jujube Mill extract can naturally protect corn from fungi.
research Identificação e cultivo de células somáticas do folículo das penas como fonte para banco de recursos biológicos de espécies de aves selvagens
The study focused on the identification and cultivation of somatic cells from feather follicles as a source for a biological resource bank for wild bird species. The research aimed to establish a method for preserving genetic material from these species, which could be crucial for conservation efforts. By successfully isolating and cultivating these cells, the study provided a potential tool for maintaining biodiversity and supporting the conservation of avian species. This approach offered a novel way to create a repository of genetic resources that could be used for future research and conservation initiatives.
research Idiopathic seasonal alopecia in horse: case report
This case report describes the first documented instance of idiopathic seasonal alopecia in a horse in Brazil, characterized by symmetrical hair loss and subsequent regrowth linked to seasonal changes.
research Identification and characterization of circRNAs in the skin during the wool follicle development of Aohan fine wool sheep
In this study, researchers identified and analyzed 8,753 circular RNAs in Aohan fine wool sheep, suggesting that certain circRNAs may play a crucial role in regulating wool follicle growth.
research Identification of Platelet Rich Plasma (PRP) Hair losses Prevent: A Study in Birdem General Hospital, Dhaka, Bangladesh
In this observational and interventional study conducted in Dhaka, Bangladesh, PRP treatment led to clinical improvements in hair count, thickness, and density among 20 out of 30 male patients with androgenetic alopecia, with significant statistical support (p-value 0.00) following 2-3 treatment sessions.
research Hair Loss in Laboratory Bred Macaques: An Idiopathic Disorder of Major Consequence
This review discusses alopecia in nonhuman primates in research settings and reports no new findings, emphasizing documentation and therapeutic intervention importance during regulatory inspections.
research 1392 Activation of Id2 gene regulatory network ruling quiescence of hair follicle stem cells
In this study using a transgenic mouse model, Id2 overexpression in hair follicle stem cells prolonged quiescence by affecting gene expression, partly independent from BMP signaling.
research 879 Molecular network of Smads and Id2 genes in hair follicle stem cells regulation
In this study, researchers demonstrated that the Id2 gene acts as a direct target and effector of BMP signaling, playing a key role in maintaining quiescence in hair follicle stem cells in vivo.
research Identification of Cashmere and Other Animal Hair Fibers in Textiles by MALDI-TOF Mass Spectrometry
This study highlights that dyeing and other processing methods can impact the identification of animal species from hair fibers using an amino acid sequence analysis technique.
research Insulin resistance and hair disorders, idiopathic hirsutism, and androgenic alopecia
There is no significant link between insulin resistance and certain hair disorders like idiopathic hirsutism and androgenic alopecia.