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Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Thyroid-related genes are active in skin cells and may affect autoimmune conditions.

New treatments for skin conditions in children include a preferred drug for birthmark reduction, proactive creams for eczema and vitiligo, a safe psoriasis medication, and special tissues and socks for eczema and fungal infections.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.

Caffeine may help reduce stress-induced hair loss.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Stress can worsen skin conditions by affecting hormone levels and immune response.

People with alopecia areata have higher insulin resistance.

Finasteride exposure harms tadpole reproduction and hormone balance.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Testosterone therapy may improve mood, well-being, and sexual function in premenopausal women, but more research is needed on its long-term safety and effectiveness.

Women with PCOS have higher hair cortisol levels, which are linked to worse metabolic and inflammatory conditions.

A new gene variant causes glucocorticoid resistance in a mother and son.

A thorough initial check-up is essential before sperm banking to ensure the best chance of preserving good quality sperm.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

Early detection and treatment of PCOS in teenagers is important to manage symptoms and prevent severe issues.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Girls with PCOS during adolescence have a higher risk of developing type 2 diabetes, and early treatment can help manage this risk.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

Hair growth and health are influenced by stress and hormones.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.

Aquaporins could be new drug targets for treating polycystic ovary syndrome.

The document concludes that early and personalized treatment for PCOS in adolescents is crucial to manage symptoms and prevent long-term health issues.

Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.