This study reported that severe hypothyroidism in two pediatric patients was associated with transient liver and kidney dysfunction, which resolved after beginning levothyroxine treatment.
1 citations
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October 2018 in “The American journal of gastroenterology” This case report describes a 29-year-old male with relapsing hepatitis A, a rare complication of acute hepatitis A virus infection, characterized by prolonged elevated liver chemistries and persistent HAV IgM, managed conservatively.
1 citations
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October 2022 in “International journal of endocrinology” This study found that dihydrotestosterone treatment in female rats altered anterior pituitary gland gene expression, with significant repression of prolactin and inhibition of GnRH receptor gene expression, suggesting specific hormone production changes.
1 citations
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July 2023 in “Frontiers in Immunology” This review highlights the role of chronic stress, oxidative stress, and immune processes in the development of Hashimoto’s thyroiditis and polycystic ovary syndrome, emphasizing the potential of antioxidants in their treatment based on the existing literature.
7 citations
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October 2020 in “Wiener medizinische Wochenschrift” This paper presents a case study of a 21-year-old male with thyroid hemiagenesis, where the left thyroid lobe and isthmus are absent, and discusses the anomaly's potential clinical consequences based on existing literature.
October 2023 in “Journal of the Endocrine Society” In this case report, a shift from Hashimoto's thyroiditis to Graves' disease was observed in a 62-year-old woman, highlighting the rare transformation from hypothyroidism to hyperthyroidism over 20 years, possibly due to changes in antibody activity, according to the researchers.
October 2024 in “Journal of the Endocrine Society” This case report discusses a Korean woman who experienced recurrent episodes of painless thyroiditis over 22 years, highlighting the challenges in management due to a lack of established guidelines.
August 2026 in “European Journal of Endocrinology” In this case report, researchers described how autoimmune thyroid disease can obscure primary hyperparathyroidism diagnosis, emphasizing the necessity of combining imaging, cytology, biochemical assessment, and parathyroid scintigraphy for accurate diagnosis.
4 citations
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January 2010 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” This study described the clinical course of six young patients with type 1 autoimmune polyglandular failure, all of whom initially presented with hypoparathyroidism followed by mucocutaneous candidiasis and adrenal failure.
October 2023 in “Journal of the Endocrine Society” This case report describes a unique instance where elevated prolactin levels from a pituitary adenoma were associated with hirsutism due to increased dihydrotestosterone, with treatment leading to normalization.
20 citations
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July 1998 in “Annals of Clinical Biochemistry International Journal of Laboratory Medicine” This case study details a 56-year-old man with initial misdiagnosed Addison's disease who was later found to have hypogonadotrophic hypogonadism and secondary hypothyroidism.
12 citations
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June 2016 in “Clinical and Molecular Hepatology” This case report describes an autoimmune hepatitis patient who achieved remission with mycophenolate mofetil and corticosteroids after intolerance to azathioprine-based therapy.
2 citations
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December 2020 in “Endocrinology, diabetes & metabolism case reports” This case study highlights the complexity of managing autoimmune polyglandular syndrome type 1, emphasizing the need for thorough clinical history, high suspicion for early diagnosis, and continuous long-term follow-up.
June 1996 in “Irish Journal of Medical Science (1971 -)” This study found a statistically significant increase in glycosylated hemoglobins among patients with adult-acquired panhypopituitarism undergoing long-term GH replacement therapy, with two developing diabetes requiring treatment.
October 2024 in “Journal of the Endocrine Society” Hypothyroidism may cause vertigo symptoms like BPPV.
2 citations
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January 2016 in “Gynecological Endocrinology” This case report describes a patient with polyglandular autoimmune syndrome type 2 diagnosed via adrenal crisis, with thyroid, adrenal, and ovarian involvement.
5 citations
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March 2023 in “Archives of dermatological research” This study found that hidradenitis suppurativa is associated with increased serum levels of hypoxia-inducible factor-1α, suggesting its role in the disease's pathogenesis and as a treatment target.
August 2023 in “Physician's journal of medicine” This review provides a detailed overview of Hashimoto thyroiditis, discussing its epidemiology, risk factors, genetic and environmental contributors, clinical presentations, diagnostic methods, and treatment options, emphasizing the importance of personalized treatment plans due to varied causes and symptoms.
This article discusses functional thyroid disorders, their symptoms, and causes, without presenting new clinical results; it describes hypothyroidism and hyperthyroidism manifestations and explores the prevalence of thyroid nodules.
3 citations
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January 2024 in “Liver International” This study by Dr. Manka and colleagues reported that thyroid hormones play a significant role in regulating hepatic stellate cells, influencing liver fibrosis progression via TGFβ signaling. They found that TRα signaling might enhance scar-free tissue regeneration, offering potential pathways for targeted liver fibrosis treatments.
May 2024 in “Journal of clinical case studies reviews & reports” This case report detailed a unique instance of hypopituitarism in a 65-year-old male presenting with symptoms including nausea, vomiting, and fatigue, attributed to secondary adrenal insufficiency, which improved following appropriate cortisol treatment.
35 citations
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June 2015 in “Pediatrics in Review” This article discusses hyperthyroidism in children, highlighting Graves' disease as the most common cause, and underscores the importance of timely diagnosis and intervention to mitigate morbidity; no new clinical results are reported.
This chapter reviews the pathophysiology of immune checkpoint inhibitor-related endocrinopathies and examines the rationale for using advanced diabetes care technologies, like pump therapies and continuous glucose monitors, in managing these conditions.
1 citations
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October 2014 in “Journal of the American Geriatrics Society” This report describes a case of a 75-year-old woman whose diagnosis of hypopituitarism led to significant weight gain and improved physical function with treatment, highlighting the potential for overcoming frailty when investigating underlying causes in elderly patients.
In this case study, a 19-year-old woman with Henoch-Schönlein purpura, potentially triggered by hepatitis B vaccination, experienced improved symptoms after correcting low vitamin D levels and undergoing tonsillectomy, demonstrating these interventions may benefit similar patients.
May 2018 in “International Journal of Advances in Medicine” This study reports the successful management of acute liver failure in a 25-year-old woman with concurrent Hepatitis B and autoimmune hepatitis, using a combination of steroids, azathioprine, and tenofovir disoproxil fumarate.
October 2024 in “Journal of the Endocrine Society” In this case report, a 70-year-old woman with a history of autoimmune hypothyroidism experienced alternating hypothyroidism and hyperthyroidism over a decade, highlighting the potential role of thyrotropin receptor autoantibodies in these fluctuations.
17 citations
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August 2001 in “Australasian journal of dermatology” This case report describes a 50-year-old woman who developed drug-induced hepatitis after using spironolactone for androgenetic alopecia, with symptoms resolving upon discontinuation.
November 2024 in “Neliti” This review discusses the difficulty of diagnosing hypothyroidism due to its diverse, nonspecific symptoms that can vary greatly among patients and often mimic other conditions, which may require healthcare providers to be vigilant across various specialties to recognize and diagnose the condition effectively.
April 2020 in “BMC endocrine disorders” This case report describes a 65-year-old woman with childhood-onset growth hormone deficiency who developed panhypopituitarism, including late-onset secondary hypoadrenocorticism, affecting her respiratory and renal function.