research Genetics
Certain gene mutations can weaken the skin barrier and, when combined with environmental factors, lead to eczema and severe itching.
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research TNF-Alpha in Nonscarring Inflammatory Alopecia
TNF-a may not be as involved in certain types of hair loss as previously thought.
research Prostate Cancer and Androgenic Alopecia
The document suggests more research is needed to understand the link between baldness and prostate cancer.
research Serum Triglyceride Concentration and Risk of Prostate Cancer: A Prospective Multicenter Study
Serum triglyceride levels are not linked to prostate cancer risk.
research Androgenic Alopecia and Hirsutism in a 73-Year-Old Woman: Careful Re-Evaluation of Normal Imaging Findings May Lead to a Rare Diagnosis
A 73-year-old woman's unusual hair loss and growth led to the discovery of a rare condition causing too much testosterone, which improved after her ovaries were removed.
research Stem Cells of Hair Follicles Micrografted into a Tissue-Engineered Dermal Template (Integra)
The treatment successfully integrated hair follicles into a dermal template, showing new hair growth and blood vessel formation.
research Prostate Specific Antigen Levels in Diabetic and Non-Diabetic Men from the 2001–2002 National Health and Nutrition Examination Survey
Long-term diabetes is linked to lower prostate cancer risk.
research Pathogenesis of Alopecia Areata in C3H/HeJ Mice and DEBR Rats
Alopecia areata is an autoimmune disease that targets hair follicles.
research Agitation as a Paradoxical Effect of Divalproex Sodium: A Case Report
Divalproex sodium can unexpectedly cause agitation and hyperactivity in some patients.
research Side Effects of Topical Ophthalmic Beta-Blockers: Association with Alopecia
Eye drops with β-blockers may cause hair loss.
research Vitamin D Level in Female Pattern Hair Loss with Normal Androgen Level
Lower vitamin D levels may contribute to female hair loss.
research Variation in Male Sex Hormone Levels Among the Pattern Subtypes of Hair Loss in Patients With Androgenetic Alopecia
Different hair loss patterns may be linked to varying male hormone levels.
research Inositol and FSH: A New Frontier for Androgenetic Alopecia Treatment
Inositol and folic acid treatment significantly reduced hair loss and other symptoms in patients with androgenetic alopecia, but more research is needed for confirmation.
research The Ludwig Pattern of Androgenetic Alopecia Is Due to a Hierarchy of Androgen Sensitivity Within Follicular Units That Leads to Selective Miniaturization and a Reduction in the Number of Terminal Hairs Per Follicular Unit
Ludwig pattern hair loss results from varying androgen sensitivity, causing fewer thick hairs and more thin hairs.
research The Rotterdam Study: 2012 Objectives and Design Update
The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.
research WNT Signaling in Disease
The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
research Novel Insights Into the Pathways Regulating the Canine Hair Cycle and Their Deregulation in Alopecia X
The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.
research Fine Structure and Immunocytochemistry of Monotreme Hairs, with Emphasis on the Inner Root Sheath and Trichohyalin-Based Cornification During Hair Evolution
Monotreme hair structure and protein distribution are similar to other mammals, but their inner root sheath cornifies differently, suggesting a unique evolution from reptile skin.
research Recent Developments in Alopecias
Recent hair loss research shows some progress, especially in understanding male pattern baldness, but effective treatments for many types of hair loss are still lacking.
research Transgenerational Transmission of Reproductive and Metabolic Dysfunction in Male Progeny of Polycystic Ovary Syndrome
Sons of mothers with polycystic ovary syndrome (PCOS) have a higher risk of obesity and insulin resistance, possibly due to certain genes and factors passed down from their mothers.
research Case Report: Hair Care Routine to Treat Telogen Effluvium Associated With Post-COVID-19 Infection
A woman's COVID-19 related hair loss improved after using a specific hair care routine for 30 days.
research S1 Opioid Receptor Agonists and Serum Prostate-Specific Antigen Level: Is There a Role for Prostate Cancer Control and Chemoprevention?
Opioid use may lower PSA levels, suggesting a possible role in prostate cancer control; PSA testing is useful for detecting prostate cancer; serum triglycerides are not linked to prostate cancer risk; and higher urethral PSA levels may be associated with local hormone activity.
research Viewpoint 3
Oxidative stress plays a significant role in vitiligo, and both skin and non-skin cells may be involved.
research Aging Skin: A Window to the Body
Skin aging reflects overall body aging and can indicate internal health conditions.
research A Cell Membrane-Level Approach to Cicatricial Alopecia Management: Is Caveolin-1 a Viable Therapeutic Target in Frontal Fibrosing Alopecia?
Targeting the protein Caveolin-1 might help treat a type of scarring hair loss called Frontal Fibrosing Alopecia.
research Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity
Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
research Sequence And Structure Based Assessment Of Non-Synonymous SNPs In Hypertrichosis Universalis
Two specific SNPs in the TRPS1 gene cause excessive hair growth by altering the protein's structure.
research T-Cell Induced-Self MHC Class I/Peptide Complexes May Enable De Novo Tolerance Induction to Neo-Antigens Occurring Outside of the Thymus
Hair follicles may help teach the immune system to tolerate new self-antigens, but this can sometimes cause hair loss.
research Facial Determinants of Female Gender and Feminizing Forehead Cranioplasty
Forehead modification greatly increases the perception of femininity and is a safe procedure.
research Adipocyte-Myofibroblast Transition as a Possible Pathophysiological Step in Androgenetic Alopecia
AMT may cause hair loss and changing dWAT activity could help treat it.