May 2025 in “Journal of the ASEAN Federation of Endocrine Societies” This case study highlights the aggressive progression and complex management challenges of metastatic insulinomas, with an emphasis on considering early systemic chemotherapy and advanced therapies like everolimus and PRRT for improved outcomes.
5 citations
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September 2012 in “Journal of Investigative Dermatology” This study found that knocking down P-cadherin expression in cultured human hair follicles recreates the hair abnormalities seen in patients with hypotrichosis with juvenile macular dystrophy.
2 citations
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August 2022 in “Middle East Fertility Society Journal” This study found that combining fructose and DHT in rats successfully mimicked the clinical phenotypes of non-lean PCOS, providing a novel rodent model for this condition.
PTHrP is important for bone formation and may be targeted for osteoporosis treatment and longevity therapies.
2 citations
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May 2018 in “Journal of The American Academy of Dermatology” This study examined 15 female patients with hypothyroidism to investigate the characterization of their alopecia and ruled out other causes, using medical histories, and clinical, trichoscopic, and histologic findings.
116 citations
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April 2002 in “American journal of veterinary research” This study found trilostane to be an effective and generally safe treatment for improving symptoms in dogs with pituitary-dependent hyperadrenocorticism.
January 2013 in “Revista Clínica Española” This review discusses female hyperandrogenism, detailing diagnostic criteria and treatment options without reporting new study results; it emphasizes improving health and quality of life for affected women.
November 2021 in “World Family Medicine Journal /Middle East Journal of Family Medicine” In this study, levothyroxine therapy showed no significant effect on blood sugar level changes in children with growth hormone deficiency in Saudi Arabia.
3 citations
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November 2020 in “Cleveland Clinic Journal of Medicine” Eyelash loss can be a sign of thyroid problems.
March 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that the absence of Hif-p4h-2 in specific mouse skin cells disrupted hair follicle development, leading to hair loss due to irregular keratin formation and pathway signaling.
May 2023 in “The journal of sexual medicine” In this study, bilateral oophorectomy was reported as an effective treatment for normalizing androgen levels and resolving hypersexuality and related symptoms in a post-menopausal woman with ovarian hyperthecosis, suggesting its importance in addressing excess androgen production in such cases.
April 2025 in “International Journal of Homoeopathic Sciences” In this case study, individualized classical homeopathy was reported to effectively promote significant hair regrowth and improve emotional stability in a patient with alopecia areata, showcasing a potential holistic and sustainable alternative to conventional treatments.
7 citations
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July 2004 in “Endocrine practice” This case report highlights how persistent hyperphosphatemia, albeit often overlooked, can precede clinical acromegaly symptoms in women, complicating diagnosis due to overlapping features with oral contraceptive use and polycystic ovary syndrome.
15 citations
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January 2015 in “Skin Pharmacology and Physiology” This study indicates that targeting the PTH/PTHrP receptor may potentially stimulate hair growth, particularly for chemotherapy-induced alopecia, as observed in hairless and cyclophosphamide-treated mice.
2 citations
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January 1989 in “PubMed” In this study, 48% of women with androgenetic alopecia showed hypothyroidism or hyperprolactinemia after TRH stimulation, suggesting these conditions may influence androgen metabolism and contribute to hair loss.
4 citations
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November 2021 in “Frontiers in endocrinology” This study systematically compared pediatric and adult Cushing's disease patients, revealing more severe and earlier-onset symptoms in males, and distinct gender-specific clinical manifestations.
This case study describes a 30-year-old woman with ACTH-independent Cushing's syndrome from adrenal carcinoma, who showed significant health improvement and normalized tests 18 months after left adrenalectomy.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this case report, an 11-year-old girl with hypothyroidism was found to have Hashimoto thyroiditis after presenting with hair loss, short stature, and pubertal disturbances; the study emphasizes the importance of early diagnosis and personalized thyroid hormone therapy for better outcomes.
26 citations
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January 1982 in “Hormone Research” This study found that plasma androgen levels tend to be lower than normal in patients with multiple pituitary hormone deficiencies, particularly those with ACTH deficiencies, and that human growth hormone treatment does not affect adrenal androgen secretion.
November 2022 in “Journal of the Endocrine Society” This case study reports a rare instance of a virilizing androgen-only secreting adrenal cortical adenoma in a 13-year-old, with symptom resolution after surgical removal.
2 citations
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December 1994 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study concluded that a regimen of transdermal estradiol and oral medroxyprogesterone acetate effectively reduces hirsutism while minimizing side effects in women with polycystic ovary syndrome.
1 citations
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January 2013 in “INTAS POLIVET” In this case study, a Labrador dog diagnosed with hypothyroidism and treated with Thyroxine sodium, along with other supportive therapies, recovered completely from a generalized skin infection and alopecia within three months.
8 citations
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April 2014 in “Anti-Cancer Drugs” In this study, PTH–CBD displayed dose-dependent effects in reducing hair loss and enhancing hair regrowth in a mouse model of chemotherapy-induced alopecia.
1 citations
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January 2022 in “Open Journal of Endocrine and Metabolic Diseases” This case report describes a 70-year-old woman with pituitary resistance to thyroid hormone (PRTH) misdiagnosed as Graves disease, highlighting diagnostic challenges in managing this rare disorder.
64 citations
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August 1999 in “The American journal of medicine” This study found that while a transscrotal testosterone patch increases serum testosterone levels in hypogonadal men with AIDS and weight loss, it does not improve weight, body cell mass, or quality of life.
April 2020 in “Journal of the Endocrine Society” This case report highlights the importance of considering pituitary stalk interruption syndrome as a potential diagnosis for patients with short stature, as early detection may allow those affected to achieve normal height.
January 2015 in “Journal of clinical & experimental dermatology research” This study found that treatment with PTH-CBD stimulated hair growth in mice with alopecia areata, with increased levels of beta catenin indicating activation of the Wnt pathway.
May 2024 in “Journal of clinical case studies reviews & reports” This case report detailed a unique instance of hypopituitarism in a 65-year-old male presenting with symptoms including nausea, vomiting, and fatigue, attributed to secondary adrenal insufficiency, which improved following appropriate cortisol treatment.
2 citations
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May 2016 in “Journal of dermatology” This letter discusses tissue expansion for correcting alopecia in a child with hypohidrotic ectodermal dysplasia, but provides no new experimental results.
1 citations
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April 2023 in “International Journal of Homoeopathic Sciences” This article discusses homoeopathic management of a case of alopecia areata and reports no new clinical results.