A Case Report of Cushing's Syndrome Due to an Adrenal Carcinoma

    June 1992 in “ PubMed ”
    M. Guidi, Marco Andreani, P Signoretti, Marco Domenichini, Pignatti Morano Fm, J Locatelli, F Belbusti
    From the encyclopedia
    Hydrocortisone →

    a synthetic cortisol used for anti-inflammatory effects

    Ketoconazole →

    antifungal with some anti-androgenic benefits, often used as a shampoo

    Studysummary This case study describes a 30-year-old woman with ACTH-independent Cushing's syndrome from adrenal carcinoma, who showed significant health improvement and normalized tests 18 months after left adrenalectomy.
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    A rare case of ACTH-independent Cushing's syndrome due to adrenal carcinoma was reported in a 30-year-old woman who exhibited symptoms such as hypertension, centripetal obesity, rubeosis, and hair loss. Elevated cortisol levels and suppressed ACTH confirmed the diagnosis. Imaging revealed a mass in the left adrenal gland. The patient was treated with ketoconazole before undergoing a successful left adrenalectomy with regional lymphadenectomy. Eighteen months post-surgery, the patient was in excellent health with no signs of Cushing's syndrome and normal laboratory results.
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